SNP Detail For rs6537298
1.Mapping Information
Human SNP ID rs6537298
Human chromosome chr4
Human SNP position 144585719
Pig chromosome chr8
Pig SNP position 88992166
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.21
Chromosome idchr4
Chromosome position144585719
Reported geneIntergenic
Mapped geneKRT18P51 - HHIP-AS1
Upstream gene id391703
Downstream gene id646576
SNP gene ids
Upstream gene distance12733
Downstream gene distance57197
SNP risk allelers6537298-T
SNPsrs6537298
Merged0
SNP id current6537298
Contextintergenic_variant
Intergenic1
Allele frequency0.572
P value0.000000003
Pvalue mlog8.52287874528033
P value text
Or beta0.051
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q31.21
Chromosome idchr4
Chromosome position144585719
Reported geneIntergenic
Mapped geneKRT18P51 - HHIP-AS1
Upstream gene id391703
Downstream gene id646576
SNP gene ids
Upstream gene distance12733
Downstream gene distance57197
SNP risk allelers6537298-T
SNPsrs6537298
Merged0
SNP id current6537298
Contextintergenic_variant
Intergenic1
Allele frequency0.572
P value0.0000000002
Pvalue mlog9.69897000433601
P value text
Or beta0.011
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264