SNP Detail For rs652888
1.Mapping Information
Human SNP ID rs652888
Human chromosome chr6
Human SNP position 31883457
Pig chromosome chr7
Pig SNP position 27830732
2.Annotation Information
PubMed ID23760081
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23760081
StudyA genome-wide association study identified new variants associated with the risk of chronic hepatitis B.
Disease/TraitChronic hepatitis B infection
Initial sample400 Korean ancestry cases, 1,000 Korean ancestry controls
Replication sample971 Korean ancestry cases, 1,938 Korean ancestry controls
Region6p21.33
Chromosome idchr6
Chromosome position31883457
Reported geneEHMT2
Mapped geneEHMT2
Upstream gene id
Downstream gene id
SNP gene ids10919
Upstream gene distance
Downstream gene distance
SNP risk allelers652888-?
SNPsrs652888
Merged0
SNP id current652888
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000000000007
Pvalue mlog12.1549019599857
P value text
Or beta1.38
%95 Ci[1.22-1.57]
PlatformIllumina [719265]
CNVN
Mapped traithepatitis B infection
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004197
Study accessionGCST002068
PubMed ID21323541
JournalN Engl J Med
Linkwww.ncbi.nlm.nih.gov/pubmed/21323541
StudyRisk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.
Disease/TraitIdiopathic membranous nephropathy
Initial sample556 European ancestry cases, 2,338 European ancestry controls
Replication sampleNA
Region6p21.33
Chromosome idchr6
Chromosome position31883457
Reported geneEHMT2
Mapped geneEHMT2
Upstream gene id
Downstream gene id
SNP gene ids10919
Upstream gene distance
Downstream gene distance
SNP risk allelers652888-C
SNPsrs652888
Merged0
SNP id current652888
Contextintron_variant
Intergenic0
Allele frequency0.2021
P value3E-46
Pvalue mlog45.5228787452803
P value text
Or beta2.71
%95 Ci[NR]
PlatformIllumina [242824]
CNVN
Mapped traitmembranous glomerulonephritis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004254
Study accessionGCST000984
PubMed ID25802187
JournalHepatology
Linkwww.ncbi.nlm.nih.gov/pubmed/25802187
StudyGenetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.
Disease/TraitChronic hepatitis B infection
Initial sample2,514 Chinese ancestry cases, 1,130 Chinese ancestry controls
Replication sample6,600 Chinese ancestry cases, 8,127 Chinese ancestry controls
Region6p21.33
Chromosome idchr6
Chromosome position31883457
Reported geneEHMT2
Mapped geneEHMT2
Upstream gene id
Downstream gene id
SNP gene ids10919
Upstream gene distance
Downstream gene distance
SNP risk allelers652888-G
SNPsrs652888
Merged0
SNP id current652888
Contextintron_variant
Intergenic0
Allele frequency0.24
P value0.000001
Pvalue mlog6
P value text
Or beta1.14
%95 Ci[1.08-1.19]
PlatformIllumina [3680900] (imputed)
CNVN
Mapped traitchronic hepatitis B infection
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004239
Study accessionGCST002879