Human SNP ID | rs647161 |
---|---|
Human chromosome | chr5 |
Human SNP position | 135163402 |
Pig chromosome | chr2 |
Pig SNP position | 142790986 |
PubMed ID | 23263487 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23263487 |
Study | Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. |
Disease/Trait | Colorectal cancer |
Initial sample | 2,098 East Asian ancestry cases, 5,749 East Asian ancestry controls |
Replication sample | 5,358 East Asian ancestry cases, 5,922 East Asian ancestry controls, 26,060 European ancestry individuals |
Region | 5q31.1 |
Chromosome id | chr5 |
Chromosome position | 135163402 |
Reported gene | CATSPER3, PCBD2, MIR4461 and H2AFY, PITX1 |
Mapped gene | C5orf66 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 100996485 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs647161-A |
SNPs | rs647161 |
Merged | 0 |
SNP id current | 647161 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.667 |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | |
Or beta | 1.11 |
%95 Ci | [1.08-1.15] |
Platform | Affymetrix, Illumina [1636380] (imputed) |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST001792 |
PubMed ID | 23263487 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23263487 |
Study | Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. |
Disease/Trait | Colorectal cancer |
Initial sample | 2,098 East Asian ancestry cases, 5,749 East Asian ancestry controls |
Replication sample | 5,358 East Asian ancestry cases, 5,922 East Asian ancestry controls, 26,060 European ancestry individuals |
Region | 5q31.1 |
Chromosome id | chr5 |
Chromosome position | 135163402 |
Reported gene | CATSPER3, PCBD2, MIR4461 and H2AFY, PITX1 |
Mapped gene | C5orf66 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 100996485 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs647161-A |
SNPs | rs647161 |
Merged | 0 |
SNP id current | 647161 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.313 |
P value | 0.0000000004 |
Pvalue mlog | 9.39794000867203 |
P value text | (East Asian) |
Or beta | 1.17 |
%95 Ci | [1.11-1.22] |
Platform | Affymetrix, Illumina [1636380] (imputed) |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST001792 |
PubMed ID | 24836286 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24836286 |
Study | Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. |
Disease/Trait | Colorectal cancer |
Initial sample | 2,098 East Asian ancestry cases, 6,172 East Asian ancestry controls |
Replication sample | 12,865 East Asian ancestry cases, 25,773 East Asian ancestry controls, up to 16,984 European ancestry cases, up to 18,262 European ancestry controls |
Region | 5q31.1 |
Chromosome id | chr5 |
Chromosome position | 135163402 |
Reported gene | PITX1 |
Mapped gene | C5orf66 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 100996485 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs647161-A |
SNPs | rs647161 |
Merged | 0 |
SNP id current | 647161 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.31 |
P value | 0.00000000000002 |
Pvalue mlog | 13.698970004336 |
P value text | (East Asian) |
Or beta | 1.15 |
%95 Ci | [1.11-1.19] |
Platform | Affymetrix, Illumina [2400000] (imputed) |
CNV | N |
Mapped trait | colorectal cancer |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005842 |
Study accession | GCST002454 |