Human SNP ID | rs6448119 |
---|---|
Human chromosome | chr4 |
Human SNP position | 22089761 |
Pig chromosome | chr8 |
Pig SNP position | 16802805 |
PubMed ID | 21156761 |
---|---|
Journal | Ann Rheum Dis |
Link | www.ncbi.nlm.nih.gov/pubmed/21156761 |
Study | A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. |
Disease/Trait | Rheumatoid arthritis |
Initial sample | 1,147 European ancestry ACPA positive RA cases, 774 European ancestry ACPA negative RA cases, 1,079 European ancestry controls |
Replication sample | 887 European ancestry ACPA positive RA cases, 1,218 European ancestry controls |
Region | 4p15.2 |
Chromosome id | chr4 |
Chromosome position | 22089761 |
Reported gene | KCNIP4, GPR125 |
Mapped gene | KCNIP4 - LOC100505912 |
Upstream gene id | 80333 |
Downstream gene id | 100505912 |
SNP gene ids | |
Upstream gene distance | 140960 |
Downstream gene distance | 237593 |
SNP risk allele | rs6448119-? |
SNPs | rs6448119 |
Merged | 0 |
SNP id current | 6448119 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000007 |
Pvalue mlog | 5.15490195998574 |
P value text | (ACPA-positive RA vs ACPA-negative RA) |
Or beta | |
%95 Ci | |
Platform | Illumina [1723056] (imputed) |
CNV | N |
Mapped trait | rheumatoid arthritis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000685 |
Study accession | GCST000917 |