Human SNP ID | rs6432860 |
---|---|
Human chromosome | chr2 |
Human SNP position | 166041354 |
Pig chromosome | chr15 |
Pig SNP position | 81066577 |
PubMed ID | 25344690 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25344690 |
Study | Common variants associated with general and MMR vaccine-related febrile seizures. |
Disease/Trait | Febrile seizures |
Initial sample | 929 European ancestry MMR vaccine-related febrile seizures cases, 1,070 European ancestry MMR vaccine-unrelated febrile seizures cases, 4,118 European ancestry controls |
Replication sample | Up to 408 European ancestry MMR vaccine-related febrile seizures cases, Up to 1,034 European ancestry MMR vaccine-unrelated febrile seizures cases, Up to 1,645 European ancestry controls |
Region | 2q24.3 |
Chromosome id | chr2 |
Chromosome position | 166041354 |
Reported gene | SCN1A |
Mapped gene | SCN1A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6323 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6432860-G |
SNPs | rs6432860 |
Merged | 0 |
SNP id current | 6432860 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | 0.704 |
P value | 0.0000000000000002 |
Pvalue mlog | 15.698970004336 |
P value text | (Overall) |
Or beta | 1.34 |
%95 Ci | [1.25-1.43] |
Platform | Illumina [up to 8129553] (imputed) |
CNV | N |
Mapped trait | febrile seizures |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0002373 |
Study accession | GCST002672 |
PubMed ID | 25344690 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25344690 |
Study | Common variants associated with general and MMR vaccine-related febrile seizures. |
Disease/Trait | Febrile seizures (MMR vaccine-unrelated) |
Initial sample | 1,070 European ancestry cases, 4,118 European ancestry controls |
Replication sample | Up to 1,034 European ancestry cases, Up to 1,645 European ancestry controls |
Region | 2q24.3 |
Chromosome id | chr2 |
Chromosome position | 166041354 |
Reported gene | SCN1A |
Mapped gene | SCN1A |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6323 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6432860-G |
SNPs | rs6432860 |
Merged | 0 |
SNP id current | 6432860 |
Context | synonymous_variant |
Intergenic | 0 |
Allele frequency | 0.704 |
P value | 0.000000002 |
Pvalue mlog | 8.69897000433601 |
P value text | |
Or beta | 1.29 |
%95 Ci | [1.19-1.40] |
Platform | Illumina [8129384] (imputed) |
CNV | N |
Mapped trait | febrile seizures |
Mapped trait URI | http://purl.obolibrary.org/obo/HP_0002373 |
Study accession | GCST002673 |