Human SNP ID | rs643177 |
---|---|
Human chromosome | chr6 |
Human SNP position | 137874556 |
Pig chromosome | chr1 |
Pig SNP position | 29834072 |
PubMed ID | 25574825 |
---|---|
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25574825 |
Study | Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms. |
Disease/Trait | Inflammatory skin disease |
Initial sample | 2,079 European ancestry atopic dermatitis cases, 4,212 European ancestry psoriasis cases, 11,899 European ancestry controls |
Replication sample | NA |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137874556 |
Reported gene | TNFAIP3 |
Mapped gene | TNFAIP3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7128 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs643177-? |
SNPs | rs643177 |
Merged | 0 |
SNP id current | 643177 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | NR |
P value | 0.0000000000000009 |
Pvalue mlog | 15.0457574905606 |
P value text | (Psoriasis) |
Or beta | 1.27 |
%95 Ci | [1.20鈥?.34] |
Platform | Affymetrix, Illumina [~ 5200000] |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002740 |
PubMed ID | 25903422 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25903422 |
Study | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. |
Disease/Trait | Psoriasis |
Initial sample | 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls |
Replication sample | 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137874556 |
Reported gene | TNFAIP3 |
Mapped gene | TNFAIP3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7128 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs643177-T |
SNPs | rs643177 |
Merged | 0 |
SNP id current | 643177 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.273 |
P value | 0.0000000005 |
Pvalue mlog | 9.30102999566398 |
P value text | (EA) |
Or beta | 1.24 |
%95 Ci | [1.16-1.33] |
Platform | Illumina [up to 4778154] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002874 |
PubMed ID | 25903422 |
Journal | Nat Commun |
Link | www.ncbi.nlm.nih.gov/pubmed/25903422 |
Study | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. |
Disease/Trait | Psoriasis |
Initial sample | 3,496 European ancestry cases, 5,186 European ancestry controls, 1,588 Chinese ancestry cases, 3,546 Chinese ancestry controls |
Replication sample | 5,134 European ancestry cases, 5,633 European ancestry controls, 5,151 Chinese ancestry cases, 5,152 Chinese ancestry controls |
Region | 6q23.3 |
Chromosome id | chr6 |
Chromosome position | 137874556 |
Reported gene | TNFAIP3 |
Mapped gene | TNFAIP3 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7128 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs643177-T |
SNPs | rs643177 |
Merged | 0 |
SNP id current | 643177 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.273 |
P value | 0.000000000009 |
Pvalue mlog | 11.0457574905606 |
P value text | |
Or beta | 1.25 |
%95 Ci | [1.17-1.33] |
Platform | Illumina [up to 4778154] (imputed) |
CNV | N |
Mapped trait | psoriasis |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000676 |
Study accession | GCST002874 |