SNP Detail For rs6430538
1.Mapping Information
Human SNP ID rs6430538
Human chromosome chr2
Human SNP position 134782397
Pig chromosome chr15
Pig SNP position 19762802
2.Annotation Information
PubMed ID22451204
JournalAnn Neurol
Linkwww.ncbi.nlm.nih.gov/pubmed/22451204
StudyMeta-analysis of Parkinson__s disease: identification of a novel locus, RIT2.
Disease/TraitParkinson__s disease
Initial sample4,238 European ancestry cases, 4,239 European ancestry controls
Replication sample3,738 European ancestry cases, 2,111 European ancestry controls
Region2q21.3
Chromosome idchr2
Chromosome position134782397
Reported geneintergenic
Mapped geneTMEM163 - ACMSD
Upstream gene id81615
Downstream gene id130013
SNP gene ids
Upstream gene distance45973
Downstream gene distance55951
SNP risk allelers6430538-?
SNPsrs6430538
Merged0
SNP id current6430538
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.0000002
Pvalue mlog6.69897000433601
P value text
Or beta1.15
%95 Ci[NR]
PlatformIllumina [2500000] (imputed)
CNVN
Mapped traitParkinson__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002508
Study accessionGCST001430
PubMed ID25064009
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25064009
StudyLarge-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson__s disease.
Disease/TraitParkinson__s disease
Initial sample13,708 European ancestry cases, 95,282 European ancestry controls
Replication sample5,353 European ancestry cases, 5,551 European ancestry controls
Region2q21.3
Chromosome idchr2
Chromosome position134782397
Reported geneACMSD, TMEM163
Mapped geneTMEM163 - ACMSD
Upstream gene id81615
Downstream gene id130013
SNP gene ids
Upstream gene distance45973
Downstream gene distance55951
SNP risk allelers6430538-C
SNPsrs6430538
Merged0
SNP id current6430538
Contextintron_variant
Intergenic1
Allele frequency0.57
P value9E-20
Pvalue mlog19.0457574905606
P value text
Or beta1.1429
%95 Ci[1.11-1.17]
PlatformIllumina [7893274] (imputed)
CNVN
Mapped traitParkinson__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002508
Study accessionGCST002544