SNP Detail For rs6429703
1.Mapping Information
Human SNP ID rs6429703
Human chromosome chr1
Human SNP position 15013464
Pig chromosome chr6
Pig SNP position 68642945
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin)
Initial sample150 Japanese ancestry cases, 166 Japanese ancestry controls
Replication sampleNA
Region1p36.21
Chromosome idchr1
Chromosome position15013464
Reported geneRP1-21O18.1
Mapped geneKAZN
Upstream gene id
Downstream gene id
SNP gene ids23254
Upstream gene distance
Downstream gene distance
SNP risk allelers6429703-T
SNPsrs6429703
Merged0
SNP id current6429703
Contextintron_variant
Intergenic0
Allele frequency0.078
P value0.000008
Pvalue mlog5.09691001300805
P value text(Allelic model)
Or beta2.942
%95 Ci[1.802-4.804]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to carboplatin, response to paclitaxel, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097328, http://purl.obolibrary.org/obo/GO_1901555, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002006