Human SNP ID | rs6427528 |
---|---|
Human chromosome | chr1 |
Human SNP position | 160546518 |
Pig chromosome | chr4 |
Pig SNP position | 97854361 |
PubMed ID | 23555300 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23555300 |
Study | Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis. |
Disease/Trait | Response to anti-TNF treatment in rheumatoid arthritis |
Initial sample | 733 European ancestry cases |
Replication sample | 139 European ancestry cases, 151 Japanese ancestry cases |
Region | 1q23.3 |
Chromosome id | chr1 |
Chromosome position | 160546518 |
Reported gene | CD84 |
Mapped gene | CD84, LOC105371468 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 8832, 105371468 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6427528-A |
SNPs | rs6427528 |
Merged | 0 |
SNP id current | 6427528 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.08 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (Etanercept, EA) |
Or beta | |
%95 Ci | |
Platform | Illumina [~ 2000000] (imputed) |
CNV | N |
Mapped trait | response to TNF antagonist |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004653 |
Study accession | GCST001926 |