SNP Detail For rs6427528
1.Mapping Information
Human SNP ID rs6427528
Human chromosome chr1
Human SNP position 160546518
Pig chromosome chr4
Pig SNP position 97854361
2.Annotation Information
PubMed ID23555300
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23555300
StudyGenome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.
Disease/TraitResponse to anti-TNF treatment in rheumatoid arthritis
Initial sample733 European ancestry cases
Replication sample139 European ancestry cases, 151 Japanese ancestry cases
Region1q23.3
Chromosome idchr1
Chromosome position160546518
Reported geneCD84
Mapped geneCD84, LOC105371468
Upstream gene id
Downstream gene id
SNP gene ids8832, 105371468
Upstream gene distance
Downstream gene distance
SNP risk allelers6427528-A
SNPsrs6427528
Merged0
SNP id current6427528
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.08
P value0.000002
Pvalue mlog5.69897000433601
P value text(Etanercept, EA)
Or beta
%95 Ci
PlatformIllumina [~ 2000000] (imputed)
CNVN
Mapped traitresponse to TNF antagonist
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004653
Study accessionGCST001926