Human SNP ID | rs629301 |
---|---|
Human chromosome | chr1 |
Human SNP position | 109275684 |
Pig chromosome | chr4 |
Pig SNP position | 121295362 |
PubMed ID | 20686565 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | LDL cholesterol |
Initial sample | 95,454 European ancestry individuals |
Replication sample | NA |
Region | 1p13.3 |
Chromosome id | chr1 |
Chromosome position | 109275684 |
Reported gene | CELSR2, PSRC1, SORT1 |
Mapped gene | CELSR2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 1952 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs629301-G |
SNPs | rs629301 |
Merged | 0 |
SNP id current | 629301 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.22 |
P value | 1E-170 |
Pvalue mlog | 170 |
P value text | |
Or beta | 5.65 |
%95 Ci | [5.24-6.06] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST000759 |
PubMed ID | 20686565 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | Cholesterol, total |
Initial sample | 100,184 European ancestry individuals |
Replication sample | NA |
Region | 1p13.3 |
Chromosome id | chr1 |
Chromosome position | 109275684 |
Reported gene | CELSR2, PSRC1, SORT1 |
Mapped gene | CELSR2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 1952 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs629301-G |
SNPs | rs629301 |
Merged | 0 |
SNP id current | 629301 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.22 |
P value | 6E-131 |
Pvalue mlog | 130.221848749616 |
P value text | |
Or beta | 5.41 |
%95 Ci | [4.94-5.88] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | total cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004574 |
Study accession | GCST000760 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | LDL cholesterol |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 1p13.3 |
Chromosome id | chr1 |
Chromosome position | 109275684 |
Reported gene | SORT1 |
Mapped gene | CELSR2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 1952 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs629301-G |
SNPs | rs629301 |
Merged | 0 |
SNP id current | 629301 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.24 |
P value | 5E-241 |
Pvalue mlog | 240.301029995663 |
P value text | |
Or beta | 0.167 |
%95 Ci | [NR] unit decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST002222 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | Cholesterol, total |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 1p13.3 |
Chromosome id | chr1 |
Chromosome position | 109275684 |
Reported gene | SORT1 |
Mapped gene | CELSR2 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 1952 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs629301-G |
SNPs | rs629301 |
Merged | 0 |
SNP id current | 629301 |
Context | 3_prime_UTR_variant |
Intergenic | 0 |
Allele frequency | 0.24 |
P value | 2E-170 |
Pvalue mlog | 169.698970004336 |
P value text | |
Or beta | 0.134 |
%95 Ci | [NR] unit decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | total cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004574 |
Study accession | GCST002221 |