Human SNP ID | rs6258 |
---|---|
Human chromosome | chr17 |
Human SNP position | 7631360 |
Pig chromosome | chr12 |
Pig SNP position | 55257789 |
PubMed ID | 21998597 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/21998597 |
Study | Genetic determinants of serum testosterone concentrations in men. |
Disease/Trait | Testosterone levels |
Initial sample | 8,938 European ancestry male individuals |
Replication sample | 5,491 European ancestry male individuals |
Region | 17p13.1 |
Chromosome id | chr17 |
Chromosome position | 7631360 |
Reported gene | SHBG |
Mapped gene | SHBG |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6462 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6258-T |
SNPs | rs6258 |
Merged | 0 |
SNP id current | 6258 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.02 |
P value | 2E-22 |
Pvalue mlog | 21.698970004336 |
P value text | (Testosterone) |
Or beta | 82.3 |
%95 Ci | [65.64-98.96] ng/dl decrease |
Platform | Affymetrix, Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | testosterone measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004908 |
Study accession | GCST001264 |
PubMed ID | 22829776 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/22829776 |
Study | A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. |
Disease/Trait | Sex hormone-binding globulin levels |
Initial sample | 21,791 European ancestry individuals |
Replication sample | 8,175 European ancestry individuals |
Region | 17p13.1 |
Chromosome id | chr17 |
Chromosome position | 7631360 |
Reported gene | SHBG |
Mapped gene | SHBG |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 6462 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6258-T |
SNPs | rs6258 |
Merged | 0 |
SNP id current | 6258 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.02 |
P value | 3E-46 |
Pvalue mlog | 45.5228787452803 |
P value text | (Men + Women, Conditional) |
Or beta | 0.272 |
%95 Ci | [0.24-0.31] unit decrease |
Platform | Affymetrix, Illumina [2543887] (imputed) |
CNV | N |
Mapped trait | sex hormone globulin binding measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004696 |
Study accession | GCST001612 |