SNP Detail For rs6127921
1.Mapping Information
Human SNP ID rs6127921
Human chromosome chr20
Human SNP position 57063694
Pig chromosome chr17
Pig SNP position 64675675
2.Annotation Information
PubMed ID19846067
JournalBiol Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/19846067
StudyA genomewide association study of citalopram response in major depressive disorder.
Disease/TraitResponse to citalopram treatment
Initial sampleUp to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders
Replication sampleNA
Region20q13.31
Chromosome idchr20
Chromosome position57063694
Reported geneBMP7
Mapped geneLOC105372684 - LOC105372685
Upstream gene id105372684
Downstream gene id105372685
SNP gene ids
Upstream gene distance12167
Downstream gene distance53495
SNP risk allelers6127921-?
SNPsrs6127921
Merged0
SNP id current6127921
Contextintergenic_variant
Intergenic1
Allele frequency0.82
P value0.000003
Pvalue mlog5.52287874528033
P value text(response)
Or beta1.64
%95 Ci[1.33-2.04]
PlatformAffymetrix [430198]
CNVN
Mapped traitresponse to antidepressant
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0036276
Study accessionGCST000509
PubMed ID19846067
JournalBiol Psychiatry
Linkwww.ncbi.nlm.nih.gov/pubmed/19846067
StudyA genomewide association study of citalopram response in major depressive disorder.
Disease/TraitResponse to citalopram treatment
Initial sampleUp to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders
Replication sampleNA
Region20q13.31
Chromosome idchr20
Chromosome position57063694
Reported geneBMP7
Mapped geneLOC105372684 - LOC105372685
Upstream gene id105372684
Downstream gene id105372685
SNP gene ids
Upstream gene distance12167
Downstream gene distance53495
SNP risk allelers6127921-?
SNPsrs6127921
Merged0
SNP id current6127921
Contextintergenic_variant
Intergenic1
Allele frequency0.81
P value0.000001
Pvalue mlog6
P value text(remission)
Or beta1.75
%95 Ci[1.39-2.17]
PlatformAffymetrix [430198]
CNVN
Mapped traitresponse to antidepressant
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0036276
Study accessionGCST000509