Human SNP ID | rs6102185 |
---|---|
Human chromosome | chr20 |
Human SNP position | 40849893 |
Pig chromosome | chr17 |
Pig SNP position | 48942367 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 40849893 |
Reported gene | NR |
Mapped gene | LOC101927098 - LOC100128988 |
Upstream gene id | 101927098 |
Downstream gene id | 100128988 |
SNP gene ids | |
Upstream gene distance | 132577 |
Downstream gene distance | 130144 |
SNP risk allele | rs6102185-G |
SNPs | rs6102185 |
Merged | 0 |
SNP id current | 6102185 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.422812170677362 |
P value | 0.000002 |
Pvalue mlog | 5.69897000433601 |
P value text | (IGP25) |
Or beta | 0.1489 |
%95 Ci | [0.088-0.21] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 40849893 |
Reported gene | NR |
Mapped gene | LOC101927098 - LOC100128988 |
Upstream gene id | 101927098 |
Downstream gene id | 100128988 |
SNP gene ids | |
Upstream gene distance | 132577 |
Downstream gene distance | 130144 |
SNP risk allele | rs6102185-G |
SNPs | rs6102185 |
Merged | 0 |
SNP id current | 6102185 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.423097751558326 |
P value | 0.000001 |
Pvalue mlog | 6 |
P value text | (IGP27) |
Or beta | 0.151 |
%95 Ci | [0.09-0.212] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 40849893 |
Reported gene | NR |
Mapped gene | LOC101927098 - LOC100128988 |
Upstream gene id | 101927098 |
Downstream gene id | 100128988 |
SNP gene ids | |
Upstream gene distance | 132577 |
Downstream gene distance | 130144 |
SNP risk allele | rs6102185-G |
SNPs | rs6102185 |
Merged | 0 |
SNP id current | 6102185 |
Context | downstream_gene_variant |
Intergenic | 1 |
Allele frequency | 0.422547655372269 |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (IGP34) |
Or beta | 0.1429 |
%95 Ci | [0.082-0.204] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |