SNP Detail For rs6088765
1.Mapping Information
Human SNP ID rs6088765
Human chromosome chr20
Human SNP position 35211477
Pig chromosome chr17
Pig SNP position 43771370
2.Annotation Information
PubMed ID23128233
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/23128233
StudyHost-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Disease/TraitUlcerative colitis
Initial sampleUp to 12,924 European ancestry cases, up to 21,442 European ancestry controls
Replication sampleUp to 25,683 European ancestry cases, up to 17,015 European ancestry controls
Region20q11.22
Chromosome idchr20
Chromosome position35211477
Reported geneUQCC, CEP250, PROCR
Mapped genePROCR
Upstream gene id
Downstream gene id
SNP gene ids10544
Upstream gene distance
Downstream gene distance
SNP risk allelers6088765-G
SNPsrs6088765
Merged0
SNP id current6088765
Contextintron_variant
Intergenic0
Allele frequency0.437
P value0.00000002
Pvalue mlog7.69897000433601
P value text
Or beta1.079
%95 Ci[1.041-1.117]
PlatformAffymetrix, Illumina [1230000] (imputed)
CNVN
Mapped traitulcerative colitis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000729
Study accessionGCST001728
PubMed ID26192919
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26192919
StudyAssociation analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
Disease/TraitUlcerative colitis
Initial sample6,968 European ancestry cases, 20,464 European ancestry controls
Replication sample10,679 European ancestry cases, 26,715 European ancestry controls, 397 Iranian ancestry cases, 342 Iranian ancestry controls, 1,239 Indian ancestry cases, 990 Indian ancestry controls, 1,134 East Asian ancestry cases, 3,719 East Asian ancestry controls
Region20q11.22
Chromosome idchr20
Chromosome position35211477
Reported geneNR
Mapped genePROCR
Upstream gene id
Downstream gene id
SNP gene ids10544
Upstream gene distance
Downstream gene distance
SNP risk allelers6088765-C
SNPsrs6088765
Merged0
SNP id current6088765
Contextintron_variant
Intergenic0
Allele frequency0.4467
P value0.000001
Pvalue mlog6
P value text(EA)
Or beta1.0630414
%95 Ci[1.04-1.09]
PlatformAffymetrix, Illumina [~ 9000000] (imputed)
CNVN
Mapped traitulcerative colitis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000729
Study accessionGCST003045