Human SNP ID | rs608114 |
---|---|
Human chromosome | chr6 |
Human SNP position | 95928822 |
Pig chromosome | chr1 |
Pig SNP position | 71373337 |
PubMed ID | 25461247 |
---|---|
Journal | Pharmacogenet Genomics |
Link | www.ncbi.nlm.nih.gov/pubmed/25461247 |
Study | Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols. |
Disease/Trait | Response to abacavir-containing treatment in HIV-1 infection (virologic failure) |
Initial sample | Up 346 European ancestry individuals, Up to 265 Black individuals, Up to 175 Hispanic individuals |
Replication sample | NA |
Region | 6q16.1 |
Chromosome id | chr6 |
Chromosome position | 95928822 |
Reported gene | NR |
Mapped gene | MANEA - KRT18P50 |
Upstream gene id | 79694 |
Downstream gene id | 442236 |
SNP gene ids | |
Upstream gene distance | 319370 |
Downstream gene distance | 62276 |
SNP risk allele | rs608114-A |
SNPs | rs608114 |
Merged | 0 |
SNP id current | 608114 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | (phenotype 3) |
Or beta | 4.84 |
%95 Ci | [NR] |
Platform | Illumina [> 8000000] (imputed) |
CNV | N |
Mapped trait | HIV-1 infection, virologic response measurement, response to abacavir |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006906, http://www.ebi.ac.uk/efo/EFO_0006905 |
Study accession | GCST002769 |
PubMed ID | 25461247 |
Journal | Pharmacogenet Genomics |
Link | www.ncbi.nlm.nih.gov/pubmed/25461247 |
Study | Genome-wide association study of virologic response with efavirenz-containing or abacavir-containing regimens in AIDS clinical trials group protocols. |
Disease/Trait | Response to efavirenz-containing treatment in HIV 1 infection (virologic failure) |
Initial sample | Up to 737 European ancestry individuals, Up to 545 Black individuals, Up to 314 Hispanic individuals |
Replication sample | NA |
Region | 6q16.1 |
Chromosome id | chr6 |
Chromosome position | 95928822 |
Reported gene | NR |
Mapped gene | MANEA - KRT18P50 |
Upstream gene id | 79694 |
Downstream gene id | 442236 |
SNP gene ids | |
Upstream gene distance | 319370 |
Downstream gene distance | 62276 |
SNP risk allele | rs608114-A |
SNPs | rs608114 |
Merged | 0 |
SNP id current | 608114 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | (phenotype 1) |
Or beta | 4.84 |
%95 Ci | [NR] |
Platform | Illumina [> 8000000] (imputed) |
CNV | N |
Mapped trait | HIV-1 infection, response to efavirenz, virologic response measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0006904, http://www.ebi.ac.uk/efo/EFO_0006906 |
Study accession | GCST002771 |