SNP Detail For rs6077251
1.Mapping Information
Human SNP ID rs6077251
Human chromosome chr20
Human SNP position 7771719
Pig chromosome chr17
Pig SNP position 18619253
2.Annotation Information
PubMed ID23648065
JournalCancer Sci
Linkwww.ncbi.nlm.nih.gov/pubmed/23648065
StudyGenome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Disease/TraitAdverse response to chemotherapy (neutropenia/leucopenia) (cisplatin)
Initial sample176 Japanese ancestry cases, 471 Japanese ancestry controls
Replication sampleNA
Region20p12.3
Chromosome idchr20
Chromosome position7771719
Reported geneSFRS13AP2
Mapped geneLOC105372518 - SRSF10P2
Upstream gene id105372518
Downstream gene id171472
SNP gene ids
Upstream gene distance46723
Downstream gene distance59782
SNP risk allelers6077251-T
SNPsrs6077251
Merged0
SNP id current6077251
Contextintergenic_variant
Intergenic1
Allele frequency0.153
P value0.000003
Pvalue mlog5.52287874528033
P value text(Allelic model)
Or beta2.065
%95 Ci[1.537-2.773]
PlatformIllumina [733202]
CNVN
Mapped traitresponse to cisplatin, response to antineoplastic agent
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0072718, http://purl.obolibrary.org/obo/GO_0097327
Study accessionGCST002007