Human SNP ID | rs6065906 |
---|---|
Human chromosome | chr20 |
Human SNP position | 45925376 |
Pig chromosome | chr17 |
Pig SNP position | 53753739 |
PubMed ID | 20686565 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | HDL cholesterol |
Initial sample | 99,900 European ancestry individuals |
Replication sample | NA |
Region | 20q13.12 |
Chromosome id | chr20 |
Chromosome position | 45925376 |
Reported gene | PLTP |
Mapped gene | PLTP - PCIF1 |
Upstream gene id | 5360 |
Downstream gene id | 63935 |
SNP gene ids | |
Upstream gene distance | 13012 |
Downstream gene distance | 9298 |
SNP risk allele | rs6065906-C |
SNPs | rs6065906 |
Merged | 0 |
SNP id current | 6065906 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.18 |
P value | 2E-22 |
Pvalue mlog | 21.698970004336 |
P value text | |
Or beta | 0.93 |
%95 Ci | [0.73-1.13] mg/dL decrease |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | high density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004612 |
Study accession | GCST000755 |
PubMed ID | 20686565 |
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | Triglycerides |
Initial sample | 96,598 European ancestry individuals |
Replication sample | NA |
Region | 20q13.12 |
Chromosome id | chr20 |
Chromosome position | 45925376 |
Reported gene | PLTP |
Mapped gene | PLTP - PCIF1 |
Upstream gene id | 5360 |
Downstream gene id | 63935 |
SNP gene ids | |
Upstream gene distance | 13012 |
Downstream gene distance | 9298 |
SNP risk allele | rs6065906-C |
SNPs | rs6065906 |
Merged | 0 |
SNP id current | 6065906 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.24 |
P value | 0.000000000000000005 |
Pvalue mlog | 17.3010299956639 |
P value text | |
Or beta | 3.32 |
%95 Ci | [2.5-4.14] mg/dL increase |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST000758 |
PubMed ID | 19936222 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19936222 |
Study | Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. |
Disease/Trait | Lipid metabolism phenotypes |
Initial sample | Up to 17,296 European ancestry female individuals |
Replication sample | Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls |
Region | 20q13.12 |
Chromosome id | chr20 |
Chromosome position | 45925376 |
Reported gene | PLTP |
Mapped gene | PLTP - PCIF1 |
Upstream gene id | 5360 |
Downstream gene id | 63935 |
SNP gene ids | |
Upstream gene distance | 13012 |
Downstream gene distance | 9298 |
SNP risk allele | rs6065906-? |
SNPs | rs6065906 |
Merged | 0 |
SNP id current | 6065906 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 3E-49 |
Pvalue mlog | 48.5228787452803 |
P value text | (HDL.large, whole) |
Or beta | 0.693 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [335603] |
CNV | N |
Mapped trait | lipid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004529 |
Study accession | GCST000533 |
PubMed ID | 19936222 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19936222 |
Study | Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. |
Disease/Trait | Lipid metabolism phenotypes |
Initial sample | Up to 17,296 European ancestry female individuals |
Replication sample | Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls |
Region | 20q13.12 |
Chromosome id | chr20 |
Chromosome position | 45925376 |
Reported gene | PLTP |
Mapped gene | PLTP - PCIF1 |
Upstream gene id | 5360 |
Downstream gene id | 63935 |
SNP gene ids | |
Upstream gene distance | 13012 |
Downstream gene distance | 9298 |
SNP risk allele | rs6065906-? |
SNPs | rs6065906 |
Merged | 0 |
SNP id current | 6065906 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 8E-37 |
Pvalue mlog | 36.096910013008 |
P value text | (HDL.mean.size, fasting) |
Or beta | 0.087 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [335603] |
CNV | N |
Mapped trait | lipid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004529 |
Study accession | GCST000533 |
PubMed ID | 19936222 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19936222 |
Study | Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. |
Disease/Trait | Lipid metabolism phenotypes |
Initial sample | Up to 17,296 European ancestry female individuals |
Replication sample | Up to 2,700 individuals, Up to 2,000 European ancestry cardiovascular heart disease cases and controls |
Region | 20q13.12 |
Chromosome id | chr20 |
Chromosome position | 45925376 |
Reported gene | PLTP |
Mapped gene | PLTP - PCIF1 |
Upstream gene id | 5360 |
Downstream gene id | 63935 |
SNP gene ids | |
Upstream gene distance | 13012 |
Downstream gene distance | 9298 |
SNP risk allele | rs6065906-? |
SNPs | rs6065906 |
Merged | 0 |
SNP id current | 6065906 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 1E-45 |
Pvalue mlog | 45 |
P value text | (HDL.mean.size, whole) |
Or beta | 0.083 |
%95 Ci | [NR] unit decrease |
Platform | Illumina [335603] |
CNV | N |
Mapped trait | lipid measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004529 |
Study accession | GCST000533 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | HDL cholesterol |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 20q13.12 |
Chromosome id | chr20 |
Chromosome position | 45925376 |
Reported gene | PLTP |
Mapped gene | PLTP - PCIF1 |
Upstream gene id | 5360 |
Downstream gene id | 63935 |
SNP gene ids | |
Upstream gene distance | 13012 |
Downstream gene distance | 9298 |
SNP risk allele | rs6065906-C |
SNPs | rs6065906 |
Merged | 0 |
SNP id current | 6065906 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.19 |
P value | 5E-40 |
Pvalue mlog | 39.3010299956639 |
P value text | |
Or beta | 0.059 |
%95 Ci | [NR] unit decrease |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | high density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004612 |
Study accession | GCST002223 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | Triglycerides |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 20q13.12 |
Chromosome id | chr20 |
Chromosome position | 45925376 |
Reported gene | PLTP |
Mapped gene | PLTP - PCIF1 |
Upstream gene id | 5360 |
Downstream gene id | 63935 |
SNP gene ids | |
Upstream gene distance | 13012 |
Downstream gene distance | 9298 |
SNP risk allele | rs6065906-C |
SNPs | rs6065906 |
Merged | 0 |
SNP id current | 6065906 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.19 |
P value | 2E-34 |
Pvalue mlog | 33.698970004336 |
P value text | |
Or beta | 0.053 |
%95 Ci | [NR] mg/dL increase |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | triglyceride measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004530 |
Study accession | GCST002216 |