SNP Detail For rs606458
1.Mapping Information
Human SNP ID rs606458
Human chromosome chr11
Human SNP position 64778919
Pig chromosome chr2
Pig SNP position 6523485
2.Annotation Information
PubMed ID21768215
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21768215
StudyGenome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
Disease/TraitUrate levels
Initial sample8,651 African American individuals
Replication sample1,996 African American individuals
Region11q13.1
Chromosome idchr11
Chromosome position64778919
Reported genePYGM, RASGRP2, CDC42BPG, NRXN2, MAP4K2, MEN1, SF1
Mapped geneSF1 - MAP4K2
Upstream gene id7536
Downstream gene id5871
SNP gene ids
Upstream gene distance75
Downstream gene distance10218
SNP risk allelers606458-T
SNPsrs606458
Merged0
SNP id current606458
Contextupstream_gene_variant
Intergenic1
Allele frequency0.35
P value0.00000000006
Pvalue mlog10.2218487496163
P value text(AA)
Or beta0.18
%95 Ci[NR] mg/dl decrease
PlatformAffymetrix [NR] (imputed)
CNVN
Mapped traiturate measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004531
Study accessionGCST001163