SNP Detail For rs60451608
1.Mapping Information
Human SNP ID rs60451608
Human chromosome chr6
Human SNP position 97108568
Pig chromosome chr1
Pig SNP position 72676823
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1 in COPD
Initial sample5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases
Replication sampleNA
Region6q16.1
Chromosome idchr6
Chromosome position97108568
Reported geneKLHL32
Mapped geneKLHL32
Upstream gene id
Downstream gene id
SNP gene ids114792
Upstream gene distance
Downstream gene distance
SNP risk allelers60451608-G
SNPsrs60451608
Merged0
SNP id current60451608
Contextintron_variant
Intergenic0
Allele frequency0.972
P value0.000002
Pvalue mlog5.69897000433601
P value text(AA)
Or beta0.369
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator, chronic obstructive pulmonary disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341
Study accessionGCST003263
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio in COPD
Initial sample5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases
Replication sampleNA
Region6q16.1
Chromosome idchr6
Chromosome position97108568
Reported geneKLHL32
Mapped geneKLHL32
Upstream gene id
Downstream gene id
SNP gene ids114792
Upstream gene distance
Downstream gene distance
SNP risk allelers60451608-G
SNPsrs60451608
Merged0
SNP id current60451608
Contextintron_variant
Intergenic0
Allele frequency0.972
P value0.000001
Pvalue mlog6
P value text(AA)
Or beta0.09
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, chronic obstructive pulmonary disease, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003265