SNP Detail For rs603965
1.Mapping Information
Human SNP ID rs603965
Human chromosome chr11
Human SNP position 69648142
Pig chromosome chr2
Pig SNP position 2346816
2.Annotation Information
PubMed ID23502783
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23502783
StudyThe CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Disease/TraitMultiple myeloma (IgH translocation)
Initial sampleup to 1,660 European ancestry cases, 7,306 European ancestry controls
Replication sample
Region11q13.3
Chromosome idchr11
Chromosome position69648142
Reported geneCCND1
Mapped geneCCND1
Upstream gene id
Downstream gene id
SNP gene ids595
Upstream gene distance
Downstream gene distance
SNP risk allelers603965-G
SNPsrs603965
Merged1
SNP id current603965
Contextsplice_region_variant
Intergenic0
Allele frequency0.56
P value0.00000000008
Pvalue mlog10.096910013008
P value text(t11;14 vs. controls)
Or beta1.82
%95 Ci[1.52-2.19]
PlatformIllumina [414804] (imputed)
CNVN
Mapped traitmultiple myeloma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001378
Study accessionGCST001906
PubMed ID23502783
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23502783
StudyThe CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.
Disease/TraitMultiple myeloma (IgH translocation)
Initial sampleup to 1,660 European ancestry cases, 7,306 European ancestry controls
Replication sample
Region11q13.3
Chromosome idchr11
Chromosome position69648142
Reported geneCCND1
Mapped geneCCND1
Upstream gene id
Downstream gene id
SNP gene ids595
Upstream gene distance
Downstream gene distance
SNP risk allelers603965-G
SNPsrs603965
Merged1
SNP id current603965
Contextsplice_region_variant
Intergenic0
Allele frequency0.55
P value0.00000000002
Pvalue mlog10.698970004336
P value text(t11;14 vs non t11;14)
Or beta1.95
%95 Ci[1.61-2.38]
PlatformIllumina [414804] (imputed)
CNVN
Mapped traitmultiple myeloma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001378
Study accessionGCST001906