SNP Detail For rs6029526
1.Mapping Information
Human SNP ID rs6029526
Human chromosome chr20
Human SNP position 41043978
Pig chromosome chr17
Pig SNP position 49119563
2.Annotation Information
PubMed ID20686565
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/20686565
StudyBiological, clinical and population relevance of 95 loci for blood lipids.
Disease/TraitLDL cholesterol
Initial sample95,454 European ancestry individuals
Replication sampleNA
Region20q12
Chromosome idchr20
Chromosome position41043978
Reported geneTOP1
Mapped geneTOP1
Upstream gene id
Downstream gene id
SNP gene ids7150
Upstream gene distance
Downstream gene distance
SNP risk allelers6029526-A
SNPsrs6029526
Merged0
SNP id current6029526
Contextintron_variant
Intergenic0
Allele frequency0.47
P value3E-19
Pvalue mlog18.5228787452803
P value text
Or beta1.41
%95 Ci[1.08-1.74] mg/dL increase
PlatformAffymetrix, Illumina, Perlegen [~ 2600000] (imputed)
CNVN
Mapped traitlow density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004611
Study accessionGCST000759
PubMed ID24097068
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24097068
StudyDiscovery and refinement of loci associated with lipid levels.
Disease/TraitLDL cholesterol
Initial sample94,595 European ancestry individuals
Replication sample93,982 European ancestry individuals
Region20q12
Chromosome idchr20
Chromosome position41043978
Reported geneTOP1
Mapped geneTOP1
Upstream gene id
Downstream gene id
SNP gene ids7150
Upstream gene distance
Downstream gene distance
SNP risk allelers6029526-A
SNPsrs6029526
Merged0
SNP id current6029526
Contextintron_variant
Intergenic0
Allele frequency0.47
P value0.000000000000000005
Pvalue mlog17.3010299956639
P value text
Or beta0.044
%95 Ci[NR] unit increase
PlatformNR [NR] (imputed)
CNVN
Mapped traitlow density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004611
Study accessionGCST002222
PubMed ID24097068
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24097068
StudyDiscovery and refinement of loci associated with lipid levels.
Disease/TraitCholesterol, total
Initial sample94,595 European ancestry individuals
Replication sample93,982 European ancestry individuals
Region20q12
Chromosome idchr20
Chromosome position41043978
Reported geneTOP1
Mapped geneTOP1
Upstream gene id
Downstream gene id
SNP gene ids7150
Upstream gene distance
Downstream gene distance
SNP risk allelers6029526-A
SNPsrs6029526
Merged0
SNP id current6029526
Contextintron_variant
Intergenic0
Allele frequency0.47
P value0.0000000000000001
Pvalue mlog16
P value text
Or beta0.04
%95 Ci[NR] unit increase
PlatformNR [NR] (imputed)
CNVN
Mapped traittotal cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004574
Study accessionGCST002221