Human SNP ID | rs6029526 |
---|---|
Human chromosome | chr20 |
Human SNP position | 41043978 |
Pig chromosome | chr17 |
Pig SNP position | 49119563 |
PubMed ID | 20686565 |
---|---|
Journal | Nature |
Link | www.ncbi.nlm.nih.gov/pubmed/20686565 |
Study | Biological, clinical and population relevance of 95 loci for blood lipids. |
Disease/Trait | LDL cholesterol |
Initial sample | 95,454 European ancestry individuals |
Replication sample | NA |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 41043978 |
Reported gene | TOP1 |
Mapped gene | TOP1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7150 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6029526-A |
SNPs | rs6029526 |
Merged | 0 |
SNP id current | 6029526 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 3E-19 |
Pvalue mlog | 18.5228787452803 |
P value text | |
Or beta | 1.41 |
%95 Ci | [1.08-1.74] mg/dL increase |
Platform | Affymetrix, Illumina, Perlegen [~ 2600000] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST000759 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | LDL cholesterol |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 41043978 |
Reported gene | TOP1 |
Mapped gene | TOP1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7150 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6029526-A |
SNPs | rs6029526 |
Merged | 0 |
SNP id current | 6029526 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 0.000000000000000005 |
Pvalue mlog | 17.3010299956639 |
P value text | |
Or beta | 0.044 |
%95 Ci | [NR] unit increase |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST002222 |
PubMed ID | 24097068 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/24097068 |
Study | Discovery and refinement of loci associated with lipid levels. |
Disease/Trait | Cholesterol, total |
Initial sample | 94,595 European ancestry individuals |
Replication sample | 93,982 European ancestry individuals |
Region | 20q12 |
Chromosome id | chr20 |
Chromosome position | 41043978 |
Reported gene | TOP1 |
Mapped gene | TOP1 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 7150 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6029526-A |
SNPs | rs6029526 |
Merged | 0 |
SNP id current | 6029526 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.47 |
P value | 0.0000000000000001 |
Pvalue mlog | 16 |
P value text | |
Or beta | 0.04 |
%95 Ci | [NR] unit increase |
Platform | NR [NR] (imputed) |
CNV | N |
Mapped trait | total cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004574 |
Study accession | GCST002221 |