Human SNP ID | rs6025 |
---|---|
Human chromosome | chr1 |
Human SNP position | 169549811 |
Pig chromosome | chr4 |
Pig SNP position | 89071421 |
PubMed ID | 22672568 |
---|---|
Journal | J Thromb Haemost |
Link | www.ncbi.nlm.nih.gov/pubmed/22672568 |
Study | A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. |
Disease/Trait | Venous thromboembolism |
Initial sample | 1,503 European and other ancestry cases, 1,459 European and other ancestry controls |
Replication sample | 1,407 cases, 1,418 controls |
Region | 1q24.2 |
Chromosome id | chr1 |
Chromosome position | 169549811 |
Reported gene | F5 |
Mapped gene | F5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2153 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6025-T |
SNPs | rs6025 |
Merged | 0 |
SNP id current | 6025 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.063 |
P value | 2E-22 |
Pvalue mlog | 21.698970004336 |
P value text | |
Or beta | 3.57 |
%95 Ci | [2.76-4.60] |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | venous thromboembolism |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004286 |
Study accession | GCST001557 |
PubMed ID | 25772935 |
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25772935 |
Study | Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism. |
Disease/Trait | Venous thromboembolism |
Initial sample | 7,507 European ancestry cases, 52,632 European ancestry controls |
Replication sample | 3,009 European ancestry cases, 2,586 European ancestry controls |
Region | 1q24.2 |
Chromosome id | chr1 |
Chromosome position | 169549811 |
Reported gene | F5 |
Mapped gene | F5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2153 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6025-T |
SNPs | rs6025 |
Merged | 0 |
SNP id current | 6025 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.033 |
P value | 1E-96 |
Pvalue mlog | 96 |
P value text | |
Or beta | 3.25 |
%95 Ci | [2.91-3.64] |
Platform | Affymetrix, Illumina [6751884] (imputed) |
CNV | N |
Mapped trait | venous thromboembolism |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004286 |
Study accession | GCST002808 |
PubMed ID | 26192919 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26192919 |
Study | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. |
Disease/Trait | Inflammatory bowel disease |
Initial sample | 12,882 European ancestry cases, 21,770 European ancestry controls |
Replication sample | 25,273 European ancestry cases, 26,715 European ancestry controls, 548 Iranian ancestry cases, 342 Iranian ancestry control, 1,423 Indian ancestry cases, 990 Indian ancestry controls, 2,824 East Asian ancestry cases, 3,719 East Asian ancestry controls |
Region | 1q24.2 |
Chromosome id | chr1 |
Chromosome position | 169549811 |
Reported gene | SELP, SELE, SELL |
Mapped gene | F5 |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 2153 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs6025-G |
SNPs | rs6025 |
Merged | 0 |
SNP id current | 6025 |
Context | missense_variant |
Intergenic | 0 |
Allele frequency | 0.97 |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | (EA) |
Or beta | 1.1942284 |
%95 Ci | |
Platform | Affymetrix, Illumina [~ 9000000] (imputed) |
CNV | N |
Mapped trait | inflammatory bowel disease |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0003767 |
Study accession | GCST003043 |