SNP Detail For rs58721818
1.Mapping Information
Human SNP ID rs58721818
Human chromosome chr6
Human SNP position 137922602
Pig chromosome chr1
Pig SNP position 29799977
2.Annotation Information
PubMed ID26502338
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26502338
StudyGenetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Disease/TraitSystemic lupus erythematosus
Initial sample5,201 European ancestry cases, 9,066 European ancestry controls
Replication sampleNA
Region6q23.3
Chromosome idchr6
Chromosome position137922602
Reported geneTNFAIP3
Mapped geneTNFAIP3 - LOC105378020
Upstream gene id7128
Downstream gene id105378020
SNP gene ids
Upstream gene distance39288
Downstream gene distance22440
SNP risk allelers58721818-T
SNPsrs58721818
Merged
SNP id current58721818
Contextintergenic_variant
Intergenic1
Allele frequency
P value3E-19
Pvalue mlog18.5228787452803
P value text
Or beta1.82
%95 Ci[NR]
PlatformIllumina [> 644674] (imputed)
CNVN
Mapped traitsystemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST003156