SNP Detail For rs58649573
1.Mapping Information
Human SNP ID rs58649573
Human chromosome chr9
Human SNP position 124005148
Pig chromosome chr1
Pig SNP position 298735446
2.Annotation Information
PubMed ID25456346
JournalPsychoneuroendocrinology
Linkwww.ncbi.nlm.nih.gov/pubmed/25456346
StudyGenomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.
Disease/TraitPost-traumatic stress disorder
Initial sample940 European, Hispanic, Native American, African American, East Asian and other ancestry cases, 2,554 European, Hispanic, Native American, African American, East Asian and other ancestry trauma-exposed controls
Replication sample313 European ancestry cases, 178 European ancestry trauma-exposed controls
Region9q33.3
Chromosome idchr9
Chromosome position124005148
Reported geneLHX2
Mapped geneLOC105376267 - LOC100505588
Upstream gene id105376267
Downstream gene id100505588
SNP gene ids
Upstream gene distance5771
Downstream gene distance2527
SNP risk allelers58649573-T
SNPsrs58649573
Merged1
SNP id current58649573
Contextintron_variant
Intergenic1
Allele frequency0.441
P value0.0000009
Pvalue mlog6.04575749056067
P value text(African American)
Or beta5.277
%95 Ci[4.62-5.93]
PlatformIllumina [21693469] (imputed)
CNVN
Mapped traitpost-traumatic stress disorder
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001358
Study accessionGCST002681