SNP Detail For rs553542
1.Mapping Information
Human SNP ID rs553542
Human chromosome chr11
Human SNP position 102830645
Pig chromosome chr9
Pig SNP position 37389177
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio in COPD
Initial sample5,439 European ancestry current and former smoker cases, 821 African American current and former smoker cases
Replication sampleNA
Region11q22.2
Chromosome idchr11
Chromosome position102830645
Reported geneLOC100288077
Mapped geneWTAPP1
Upstream gene id
Downstream gene id
SNP gene ids100288077
Upstream gene distance
Downstream gene distance
SNP risk allelers553542-T
SNPsrs553542
Merged0
SNP id current553542
Contextintron_variant
Intergenic0
Allele frequency0.884
P value0.0000007
Pvalue mlog6.15490195998574
P value text
Or beta0.018
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, chronic obstructive pulmonary disease, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0000341, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003265
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region11q22.2
Chromosome idchr11
Chromosome position102830645
Reported geneLOC100288077
Mapped geneWTAPP1
Upstream gene id
Downstream gene id
SNP gene ids100288077
Upstream gene distance
Downstream gene distance
SNP risk allelers553542-T
SNPsrs553542
Merged0
SNP id current553542
Contextintron_variant
Intergenic0
Allele frequency0.885
P value0.0000002
Pvalue mlog6.69897000433601
P value text
Or beta0.016
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264