SNP Detail For rs5498
1.Mapping Information
Human SNP ID rs5498
Human chromosome chr19
Human SNP position 10285007
Pig chromosome chr2
Pig SNP position 69441003
2.Annotation Information
PubMed ID18604267
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/18604267
StudyNovel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.
Disease/TraitSoluble ICAM-1
Initial sample4,570 European ancestry female individuals
Replication sample2,008 European ancestry female individuals
Region19p13.2
Chromosome idchr19
Chromosome position10285007
Reported geneICAM1
Mapped geneICAM1
Upstream gene id
Downstream gene id
SNP gene ids3383
Upstream gene distance
Downstream gene distance
SNP risk allelers5498-A
SNPsrs5498
Merged0
SNP id current5498
Contextmissense_variant
Intergenic0
Allele frequency0.43
P value5E-25
Pvalue mlog24.3010299956639
P value text
Or beta13.22
%95 Ci[NR] umol/L increase
PlatformIllumina [336108]
CNVN
Mapped traitICAM-1 measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004520
Study accessionGCST000210
PubMed ID21533024
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21533024
StudyGenome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci.
Disease/TraitSoluble ICAM-1
Initial sample22,435 European ancestry female individuals
Replication sample9,813 individuals
Region19p13.2
Chromosome idchr19
Chromosome position10285007
Reported geneICAM1
Mapped geneICAM1
Upstream gene id
Downstream gene id
SNP gene ids3383
Upstream gene distance
Downstream gene distance
SNP risk allelers5498-G
SNPsrs5498
Merged0
SNP id current5498
Contextmissense_variant
Intergenic0
Allele frequency0.43
P value6E-89
Pvalue mlog88.2218487496163
P value text
Or beta13.8
%95 Ci[NR] ng/mL increase
PlatformIllumina [334295]
CNVN
Mapped traitICAM-1 measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004520
Study accessionGCST001047