SNP Detail For rs549280
1.Mapping Information
Human SNP ID rs549280
Human chromosome chr4
Human SNP position 74105479
Pig chromosome chr8
Pig SNP position 74286291
2.Annotation Information
PubMed ID25096241
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25096241
StudyTrans-ethnic meta-analysis of white blood cell phenotypes.
Disease/TraitWhite blood cell count
Initial sample16,843 Japanese ancestry individuals, 19,509 European ancestry individuals, 16,388 African American individuals
Replication sampleNA
Region4q13.3
Chromosome idchr4
Chromosome position74105479
Reported geneNR
Mapped geneCXCL2 - MTHFD2L
Upstream gene id2920
Downstream gene id441024
SNP gene ids
Upstream gene distance6199
Downstream gene distance8704
SNP risk allelers549280-?
SNPsrs549280
Merged0
SNP id current549280
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000000004
Pvalue mlog9.39794000867203
P value text
Or beta0.011
%95 Ci[0.0075-0.0145] unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitleukocyte count
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004308
Study accessionGCST002556
PubMed ID25096241
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25096241
StudyTrans-ethnic meta-analysis of white blood cell phenotypes.
Disease/TraitNeutrophil count
Initial sample9,802 Japanese ancestry individuals, 16,550 European ancestry individuals, 7,391 African American individuals
Replication sampleNA
Region4q13.3
Chromosome idchr4
Chromosome position74105479
Reported geneNR
Mapped geneCXCL2 - MTHFD2L
Upstream gene id2920
Downstream gene id441024
SNP gene ids
Upstream gene distance6199
Downstream gene distance8704
SNP risk allelers549280-?
SNPsrs549280
Merged0
SNP id current549280
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.000001
Pvalue mlog6
P value text
Or beta0.0204
%95 Ci[0.012-0.029] unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitneutrophil count
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004833
Study accessionGCST002557