SNP Detail For rs5370
1.Mapping Information
Human SNP ID rs5370
Human chromosome chr6
Human SNP position 12296022
Pig chromosome chr7
Pig SNP position 9158055
2.Annotation Information
PubMed ID23381795
JournalHypertension
Linkwww.ncbi.nlm.nih.gov/pubmed/23381795
StudyGenome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.
Disease/TraitCirculating vasoactive peptide levels
Initial sample3,444 European ancestry individuals
Replication sample3,230 European ancestry individuals
Region6p24.1
Chromosome idchr6
Chromosome position12296022
Reported geneEDN1
Mapped geneEDN1
Upstream gene id
Downstream gene id
SNP gene ids1906
Upstream gene distance
Downstream gene distance
SNP risk allelers5370-T
SNPsrs5370
Merged0
SNP id current5370
Contextmissense_variant
Intergenic0
Allele frequency0.22
P value1E-27
Pvalue mlog27
P value text(ET)
Or beta2.955
%95 Ci[2.42-3.49] pmol/l increase
PlatformIllumina [2269099] (imputed)
CNVN
Mapped traitvasoactive peptide measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005196
Study accessionGCST001853