SNP Detail For rs522162
1.Mapping Information
Human SNP ID rs522162
Human chromosome chr6
Human SNP position 31952140
Pig chromosome chr7
Pig SNP position 27771620
2.Annotation Information
PubMed ID23577725
JournalAnn Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23577725
StudyGenetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.
Disease/TraitAge-related macular degeneration
Initial sample1,207 European ancestry cases, 686 European ancestry controls
Replication sample122 European ancestry cases, 86 European ancestry controls
Region6p21.33
Chromosome idchr6
Chromosome position31952140
Reported geneRDBP, CFB, ATF6B, STK19
Mapped geneNELFE
Upstream gene id
Downstream gene id
SNP gene ids7936
Upstream gene distance
Downstream gene distance
SNP risk allelers522162-?
SNPsrs522162
Merged0
SNP id current522162
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.93
P value0.0000000002
Pvalue mlog9.69897000433601
P value text
Or beta2.33
%95 Ci[1.82-3.03]
PlatformAffymetrix [2543887] (imputed)
CNVN
Mapped traitage-related macular degeneration
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001365
Study accessionGCST001986
PubMed ID23577725
JournalAnn Hum Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23577725
StudyGenetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.
Disease/TraitAge-related macular degeneration (extreme sampling)
Initial sample720 European ancestry grade 5 cases, 513 European ancestry grade 1 controls
Replication sample70 European ancestry grade 5 cases, 73 European ancestry grade 1 controls
Region6p21.33
Chromosome idchr6
Chromosome position31952140
Reported geneRDBP, CFB, DKFZp779M0311
Mapped geneNELFE
Upstream gene id
Downstream gene id
SNP gene ids7936
Upstream gene distance
Downstream gene distance
SNP risk allelers522162-?
SNPsrs522162
Merged0
SNP id current522162
Context3_prime_UTR_variant
Intergenic0
Allele frequency0.93
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta2.38
%95 Ci[1.69-3.33]
PlatformAffymetrix [2543887] (imputed)
CNVN
Mapped traitage-related macular degeneration
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001365
Study accessionGCST001987