SNP Detail For rs516946
1.Mapping Information
Human SNP ID rs516946
Human chromosome chr8
Human SNP position 41661730
Pig chromosome chr17
Pig SNP position 12192470
2.Annotation Information
PubMed ID24509480
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24509480
StudyGenome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Disease/TraitType 2 diabetes
Initial sample12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ance
Replication sample21,491 European ancestry cases, 55,647 European ancestry controls
Region8p11.21
Chromosome idchr8
Chromosome position41661730
Reported geneANK1
Mapped geneANK1
Upstream gene id
Downstream gene id
SNP gene ids286
Upstream gene distance
Downstream gene distance
SNP risk allelers516946-C
SNPsrs516946
Merged0
SNP id current516946
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.77
P value0.0000002
Pvalue mlog6.69897000433601
P value text
Or beta1.1
%95 Ci[1.06-1.15]
PlatformAffymetrix, Illumina [2500000] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST002352