Human SNP ID | rs515135 |
---|---|
Human chromosome | chr2 |
Human SNP position | 21063185 |
Pig chromosome | chr3 |
Pig SNP position | 125119276 |
PubMed ID | 19060906 |
---|---|
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/19060906 |
Study | Common variants at 30 loci contribute to polygenic dyslipidemia. |
Disease/Trait | LDL cholesterol |
Initial sample | 19,840 European ancestry individuals |
Replication sample | Up to 20,623 European ancestry individuals |
Region | 2p24.1 |
Chromosome id | chr2 |
Chromosome position | 21063185 |
Reported gene | APOB |
Mapped gene | APOB - LOC105374316 |
Upstream gene id | 338 |
Downstream gene id | 105374316 |
SNP gene ids | |
Upstream gene distance | 19112 |
Downstream gene distance | 7755 |
SNP risk allele | rs515135-T |
SNPs | rs515135 |
Merged | 0 |
SNP id current | 515135 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.2 |
P value | 5E-29 |
Pvalue mlog | 28.3010299956639 |
P value text | |
Or beta | 0.16 |
%95 Ci | [0.12-0.20] s.d. decrease |
Platform | Affymetrix, Illumina [~ 2600000] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST000287 |
PubMed ID | 20864672 |
Journal | Arterioscler Thromb Vasc Biol |
Link | www.ncbi.nlm.nih.gov/pubmed/20864672 |
Study | Genetic variants influencing circulating lipid levels and risk of coronary artery disease. |
Disease/Trait | LDL cholesterol |
Initial sample | up to 17,723 European ancestry individuals |
Replication sample | up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals |
Region | 2p24.1 |
Chromosome id | chr2 |
Chromosome position | 21063185 |
Reported gene | APOB |
Mapped gene | APOB - LOC105374316 |
Upstream gene id | 338 |
Downstream gene id | 105374316 |
SNP gene ids | |
Upstream gene distance | 19112 |
Downstream gene distance | 7755 |
SNP risk allele | rs515135-A |
SNPs | rs515135 |
Merged | 0 |
SNP id current | 515135 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.19 |
P value | 2E-20 |
Pvalue mlog | 19.698970004336 |
P value text | |
Or beta | 0.04 |
%95 Ci | [0.03-0.05] unit decrease |
Platform | Affymetrix, Illumina, Perlegen [2155369] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST000807 |
PubMed ID | 25961943 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/25961943 |
Study | The impact of low-frequency and rare variants on lipid levels. |
Disease/Trait | LDL cholesterol |
Initial sample | up 62,166 European ancestry individuals |
Replication sample | NA |
Region | 2p24.1 |
Chromosome id | chr2 |
Chromosome position | 21063185 |
Reported gene | APOB |
Mapped gene | APOB - LOC105374316 |
Upstream gene id | 338 |
Downstream gene id | 105374316 |
SNP gene ids | |
Upstream gene distance | 19112 |
Downstream gene distance | 7755 |
SNP risk allele | rs515135-C |
SNPs | rs515135 |
Merged | 0 |
SNP id current | 515135 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | 0.83 |
P value | 2E-63 |
Pvalue mlog | 62.698970004336 |
P value text | |
Or beta | 0.135 |
%95 Ci | [0.12-0.15] s.d. increase |
Platform | Affymetrix, Illumina, Perlegen [up to 9657952] (imputed) |
CNV | N |
Mapped trait | low density lipoprotein cholesterol measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004611 |
Study accession | GCST002898 |