SNP Detail For rs509477
1.Mapping Information
Human SNP ID rs509477
Human chromosome chr18
Human SNP position 34979331
Pig chromosome chr6
Pig SNP position 111073666
2.Annotation Information
PubMed ID26252872
JournalPLoS One
Linkwww.ncbi.nlm.nih.gov/pubmed/26252872
StudyVariations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aå°¾1-42 Level.
Disease/TraitCerebrospinal AB1-42 levels
Initial sampleup to 189 European and other ancestry early mild cognitive impairment cases, up to 251 European and other ancestry late mild cognitive impairment cases, up to 121 European and other ancestry Alzheimer__s disease cases, up to 215 European and other ance
Replication sampleup to 3 European and other ancestry significant memory concern cases, up to 57 European and other ancestry early mild cognitive impairment cases, up to 61 European and other ancestry late mild cognitive impairment cases, up to 62 European and other an
Region18q12.1
Chromosome idchr18
Chromosome position34979331
Reported geneMAPRE2
Mapped geneMAPRE2
Upstream gene id
Downstream gene id
SNP gene ids10982
Upstream gene distance
Downstream gene distance
SNP risk allelers509477-C
SNPsrs509477
Merged
SNP id current509477
Contextintron_variant
Intergenic0
Allele frequency0.6
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta0.0653
%95 Ci[NR] unit decrease
PlatformIllumina [~ 9000000] (imputed)
CNVN
Mapped traitbeta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004670, http://www.ebi.ac.uk/efo/EFO_0006794
Study accessionGCST003072