Human SNP ID | rs502716 |
---|---|
Human chromosome | chr20 |
Human SNP position | 945754 |
Pig chromosome | chr17 |
Pig SNP position | 39028106 |
PubMed ID | 24554482 |
---|---|
Journal | J Neurovirol |
Link | www.ncbi.nlm.nih.gov/pubmed/24554482 |
Study | Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384. |
Disease/Trait | Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) |
Initial sample | 40 European ancestry cases, 37 African American cases, 13 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls |
Replication sample | NA |
Region | 20p13 |
Chromosome id | chr20 |
Chromosome position | 945754 |
Reported gene | RSP04 |
Mapped gene | LOC105372492 - RSPO4 |
Upstream gene id | 105372492 |
Downstream gene id | 343637 |
SNP gene ids | |
Upstream gene distance | 7592 |
Downstream gene distance | 12698 |
SNP risk allele | rs502716-? |
SNPs | rs502716 |
Merged | 0 |
SNP id current | 502716 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | |
P value | 0.000004 |
Pvalue mlog | 5.39794000867203 |
P value text | (Hispanic) |
Or beta | 14 |
%95 Ci | [NR] |
Platform | Illumina [936149] |
CNV | N |
Mapped trait | response to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100 |
Study accession | GCST002366 |
PubMed ID | 24554482 |
Journal | J Neurovirol |
Link | www.ncbi.nlm.nih.gov/pubmed/24554482 |
Study | Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384. |
Disease/Trait | Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy) |
Initial sample | 19 European ancestry cases, 30 African American cases, 9 Hispanic cases, 85 European ancestry controls, 49 African American controls, 30 Hispanic controls |
Replication sample | NA |
Region | 20p13 |
Chromosome id | chr20 |
Chromosome position | 945754 |
Reported gene | RSP04 |
Mapped gene | LOC105372492 - RSPO4 |
Upstream gene id | 105372492 |
Downstream gene id | 343637 |
SNP gene ids | |
Upstream gene distance | 7592 |
Downstream gene distance | 12698 |
SNP risk allele | rs502716-? |
SNPs | rs502716 |
Merged | 0 |
SNP id current | 502716 |
Context | intergenic_variant |
Intergenic | 1 |
Allele frequency | |
P value | 0.00000003 |
Pvalue mlog | 7.52287874528033 |
P value text | (Hispanic) |
Or beta | 28 |
%95 Ci | [NR] |
Platform | Illumina [936149] |
CNV | N |
Mapped trait | response to reverse transcriptase inhibitor, HIV-1 infection, peripheral neuropathy |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0061479, http://www.ebi.ac.uk/efo/EFO_0000180, http://www.ebi.ac.uk/efo/EFO_0003100 |
Study accession | GCST002365 |