Human SNP ID | rs4948496 |
---|---|
Human chromosome | chr10 |
Human SNP position | 62045858 |
Pig chromosome | chr14 |
Pig SNP position | 70606111 |
PubMed ID | 23273568 |
---|---|
Journal | Am J Hum Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23273568 |
Study | Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 1,656 Han Chinese ancestry cases, 3,394 Han Chinese ancestry controls |
Replication sample | 3,256 Han Chinese ancestry cases, 5,667 Han Chinese ancestry controls, 453 Thai ancestry cases, 963 Thai ancestry controls |
Region | 10q21.2 |
Chromosome id | chr10 |
Chromosome position | 62045858 |
Reported gene | ARID5B, RTKN2 |
Mapped gene | ARID5B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 84159 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4948496-C |
SNPs | rs4948496 |
Merged | 0 |
SNP id current | 4948496 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.63 |
P value | 0.00000000005 |
Pvalue mlog | 10.3010299956639 |
P value text | |
Or beta | 1.1765 |
%95 Ci | |
Platform | Illumina [2100739] (imputed) |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST001795 |
PubMed ID | 26502338 |
Journal | Nat Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26502338 |
Study | Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. |
Disease/Trait | Systemic lupus erythematosus |
Initial sample | 5,201 European ancestry cases, 9,066 European ancestry controls |
Replication sample | 2,018 European ancestry cases, 6,925 European ancestry controls |
Region | 10q21.2 |
Chromosome id | chr10 |
Chromosome position | 62045858 |
Reported gene | ARID5B |
Mapped gene | ARID5B |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 84159 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4948496-C |
SNPs | rs4948496 |
Merged | 0 |
SNP id current | 4948496 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | |
P value | 0.0000000001 |
Pvalue mlog | 10 |
P value text | |
Or beta | 1.14 |
%95 Ci | [1.10鈥?.19] |
Platform | Illumina [644674] |
CNV | N |
Mapped trait | systemic lupus erythematosus |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0002690 |
Study accession | GCST003155 |