SNP Detail For rs493573
1.Mapping Information
Human SNP ID rs493573
Human chromosome chr11
Human SNP position 64789582
Pig chromosome chr2
Pig SNP position 6511077
2.Annotation Information
PubMed ID21768215
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21768215
StudyGenome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.
Disease/TraitUrate levels
Initial sample8,651 African American individuals
Replication sample1,996 African American individuals
Region11q13.1
Chromosome idchr11
Chromosome position64789582
Reported geneMAP4K2
Mapped geneMAP4K2
Upstream gene id
Downstream gene id
SNP gene ids5871
Upstream gene distance
Downstream gene distance
SNP risk allelers493573-A
SNPsrs493573
Merged0
SNP id current493573
Contextsynonymous_variant
Intergenic0
Allele frequency0.03
P value0.00000000000000002
Pvalue mlog16.698970004336
P value text(AA)
Or beta0.8
%95 Ci[NR] mg/dl decrease
PlatformAffymetrix [NR] (imputed)
CNVN
Mapped traiturate measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004531
Study accessionGCST001163