SNP Detail For rs4902562
1.Mapping Information
Human SNP ID rs4902562
Human chromosome chr14
Human SNP position 68264741
Pig chromosome chr7
Pig SNP position 98295131
2.Annotation Information
PubMed ID26502338
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26502338
StudyGenetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Disease/TraitSystemic lupus erythematosus
Initial sample5,201 European ancestry cases, 9,066 European ancestry controls
Replication sample2,018 European ancestry cases, 6,925 European ancestry controls
Region14q24.1
Chromosome idchr14
Chromosome position68264741
Reported geneRAD51B
Mapped geneRAD51B
Upstream gene id
Downstream gene id
SNP gene ids5890
Upstream gene distance
Downstream gene distance
SNP risk allelers4902562-A
SNPsrs4902562
Merged
SNP id current4902562
Contextintron_variant
Intergenic0
Allele frequency
P value0.0000000006
Pvalue mlog9.22184874961635
P value text
Or beta1.14
%95 Ci[1.09鈥?.19]
PlatformIllumina [644674]
CNVN
Mapped traitsystemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST003155
PubMed ID26502338
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26502338
StudyGenetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.
Disease/TraitSystemic lupus erythematosus
Initial sample5,201 European ancestry cases, 9,066 European ancestry controls
Replication sampleNA
Region14q24.1
Chromosome idchr14
Chromosome position68264741
Reported geneRAD51B
Mapped geneRAD51B
Upstream gene id
Downstream gene id
SNP gene ids5890
Upstream gene distance
Downstream gene distance
SNP risk allelers4902562-A
SNPsrs4902562
Merged
SNP id current4902562
Contextintron_variant
Intergenic0
Allele frequency
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta1.13
%95 Ci[NR]
PlatformIllumina [> 644674] (imputed)
CNVN
Mapped traitsystemic lupus erythematosus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002690
Study accessionGCST003156