Human SNP ID | rs4887053 |
---|---|
Human chromosome | chr15 |
Human SNP position | 78420357 |
Pig chromosome | chr7 |
Pig SNP position | 53096500 |
PubMed ID | 26634245 |
---|---|
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1 |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 15q25.1 |
Chromosome id | chr15 |
Chromosome position | 78420357 |
Reported gene | Intergenic |
Mapped gene | LOC105370912 - IREB2 |
Upstream gene id | 105370912 |
Downstream gene id | 3658 |
SNP gene ids | |
Upstream gene distance | 10424 |
Downstream gene distance | 17819 |
SNP risk allele | rs4887053-A |
SNPs | rs4887053 |
Merged | 0 |
SNP id current | 4887053 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.819 |
P value | 0.0000006 |
Pvalue mlog | 6.22184874961635 |
P value text | |
Or beta | 0.056 |
%95 Ci | NR unit increase |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | forced expiratory volume, response to bronchodilator |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366 |
Study accession | GCST003262 |
PubMed ID | 26634245 |
Journal | BMC Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/26634245 |
Study | A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. |
Disease/Trait | Post bronchodilator FEV1/FVC ratio |
Initial sample | 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals |
Replication sample | NA |
Region | 15q25.1 |
Chromosome id | chr15 |
Chromosome position | 78420357 |
Reported gene | Intergenic |
Mapped gene | LOC105370912 - IREB2 |
Upstream gene id | 105370912 |
Downstream gene id | 3658 |
SNP gene ids | |
Upstream gene distance | 10424 |
Downstream gene distance | 17819 |
SNP risk allele | rs4887053-A |
SNPs | rs4887053 |
Merged | 0 |
SNP id current | 4887053 |
Context | regulatory_region_variant |
Intergenic | 1 |
Allele frequency | 0.82 |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | |
Or beta | 0.01 |
%95 Ci | unit increase |
Platform | Illumina [NR] (imputed) |
CNV | N |
Mapped trait | response to bronchodilator, FEV/FEC ratio |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713 |
Study accession | GCST003264 |