SNP Detail For rs4887053
1.Mapping Information
Human SNP ID rs4887053
Human chromosome chr15
Human SNP position 78420357
Pig chromosome chr7
Pig SNP position 53096500
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78420357
Reported geneIntergenic
Mapped geneLOC105370912 - IREB2
Upstream gene id105370912
Downstream gene id3658
SNP gene ids
Upstream gene distance10424
Downstream gene distance17819
SNP risk allelers4887053-A
SNPsrs4887053
Merged0
SNP id current4887053
Contextregulatory_region_variant
Intergenic1
Allele frequency0.819
P value0.0000006
Pvalue mlog6.22184874961635
P value text
Or beta0.056
%95 CiNR unit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region15q25.1
Chromosome idchr15
Chromosome position78420357
Reported geneIntergenic
Mapped geneLOC105370912 - IREB2
Upstream gene id105370912
Downstream gene id3658
SNP gene ids
Upstream gene distance10424
Downstream gene distance17819
SNP risk allelers4887053-A
SNPsrs4887053
Merged0
SNP id current4887053
Contextregulatory_region_variant
Intergenic1
Allele frequency0.82
P value0.000005
Pvalue mlog5.30102999566398
P value text
Or beta0.01
%95 Ciunit increase
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264