SNP Detail For rs4746822
1.Mapping Information
Human SNP ID rs4746822
Human chromosome chr10
Human SNP position 69223185
Pig chromosome chr14
Pig SNP position 78305032
2.Annotation Information
PubMed ID23903356
JournalDiabetes
Linkwww.ncbi.nlm.nih.gov/pubmed/23903356
StudyIdentification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.
Disease/TraitGlycemic traits (pregnancy)
Initial sample1,367 European ancestry individuals, 817 Hispanic individuals, 1,075 Afro-Caribbean individuals, 1,178 Thai ancestry individuals
Replication sample2,798 European ancestry individuals, 228 French Canadian founder population individuals
Region10q22.1
Chromosome idchr10
Chromosome position69223185
Reported geneSUPV3L1, SRGN, HK1, VPS26A, HKDC1
Mapped geneHKDC1, LOC101928994
Upstream gene id
Downstream gene id
SNP gene ids80201, 101928994
Upstream gene distance
Downstream gene distance
SNP risk allelers4746822-T
SNPsrs4746822
Merged0
SNP id current4746822
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.675
P value1E-22
Pvalue mlog22
P value text(2HPG)
Or beta0.28
%95 Ci[NR] unit increase
PlatformIllumina [up to 945994] (imputed)
CNVN
Mapped traitglucose tolerance test
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004307
Study accessionGCST002110