Human SNP ID | rs4720952 |
---|---|
Human chromosome | chr7 |
Human SNP position | 11251773 |
Pig chromosome | chr9 |
Pig SNP position | 88904987 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 7p21.3 |
Chromosome id | chr7 |
Chromosome position | 11251773 |
Reported gene | NR |
Mapped gene | PHF14 - NPM1P11 |
Upstream gene id | 9678 |
Downstream gene id | 10836 |
SNP gene ids | |
Upstream gene distance | 81945 |
Downstream gene distance | 5602 |
SNP risk allele | rs4720952-G |
SNPs | rs4720952 |
Merged | 0 |
SNP id current | 4720952 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.419193108861898 |
P value | 0.0000003 |
Pvalue mlog | 6.52287874528033 |
P value text | (IGP12) |
Or beta | 0.1583 |
%95 Ci | [0.098-0.219] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 7p21.3 |
Chromosome id | chr7 |
Chromosome position | 11251773 |
Reported gene | NR |
Mapped gene | PHF14 - NPM1P11 |
Upstream gene id | 9678 |
Downstream gene id | 10836 |
SNP gene ids | |
Upstream gene distance | 81945 |
Downstream gene distance | 5602 |
SNP risk allele | rs4720952-G |
SNPs | rs4720952 |
Merged | 0 |
SNP id current | 4720952 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.419614749097473 |
P value | 0.0000007 |
Pvalue mlog | 6.15490195998574 |
P value text | (IGP52) |
Or beta | 0.1534 |
%95 Ci | [0.093-0.214] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 7p21.3 |
Chromosome id | chr7 |
Chromosome position | 11251773 |
Reported gene | NR |
Mapped gene | PHF14 - NPM1P11 |
Upstream gene id | 9678 |
Downstream gene id | 10836 |
SNP gene ids | |
Upstream gene distance | 81945 |
Downstream gene distance | 5602 |
SNP risk allele | rs4720952-G |
SNPs | rs4720952 |
Merged | 0 |
SNP id current | 4720952 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | 0.419614954873646 |
P value | 0.0000004 |
Pvalue mlog | 6.39794000867203 |
P value text | (IGP73) |
Or beta | 0.1566 |
%95 Ci | [0.096-0.217] unit decrease |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |