Human SNP ID | rs4710520 |
---|---|
Human chromosome | chr6 |
Human SNP position | 65468587 |
Pig chromosome | chr1 |
Pig SNP position | 52279630 |
PubMed ID | 23382691 |
---|---|
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6q12 |
Chromosome id | chr6 |
Chromosome position | 65468587 |
Reported gene | NR |
Mapped gene | EYS |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 346007 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4710520-C |
SNPs | rs4710520 |
Merged | 0 |
SNP id current | 4710520 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.00803558 |
P value | 0.000006 |
Pvalue mlog | 5.22184874961635 |
P value text | (IGP36) |
Or beta | 2.107 |
%95 Ci | [1.2-3.02] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6q12 |
Chromosome id | chr6 |
Chromosome position | 65468587 |
Reported gene | NR |
Mapped gene | EYS |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 346007 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4710520-C |
SNPs | rs4710520 |
Merged | 0 |
SNP id current | 4710520 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.00804562 |
P value | 0.000003 |
Pvalue mlog | 5.52287874528033 |
P value text | (IGP37) |
Or beta | 2.1675 |
%95 Ci | [1.26-3.08] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |
PubMed ID | 23382691 |
Journal | PLoS Genet |
Link | www.ncbi.nlm.nih.gov/pubmed/23382691 |
Study | Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. |
Disease/Trait | IgG glycosylation |
Initial sample | 2,247 European ancestry individuals |
Replication sample | NA |
Region | 6q12 |
Chromosome id | chr6 |
Chromosome position | 65468587 |
Reported gene | NR |
Mapped gene | EYS |
Upstream gene id | |
Downstream gene id | |
SNP gene ids | 346007 |
Upstream gene distance | |
Downstream gene distance | |
SNP risk allele | rs4710520-C |
SNPs | rs4710520 |
Merged | 0 |
SNP id current | 4710520 |
Context | intron_variant |
Intergenic | 0 |
Allele frequency | 0.00803558 |
P value | 0.000005 |
Pvalue mlog | 5.30102999566398 |
P value text | (IGP38) |
Or beta | 2.1251 |
%95 Ci | [1.21-3.04] unit increase |
Platform | Illumina [~ 2500000] (imputed) |
CNV | N |
Mapped trait | serum IgG glycosylation measurement |
Mapped trait URI | http://www.ebi.ac.uk/efo/EFO_0005193 |
Study accession | GCST001848 |