SNP Detail For rs4710520
1.Mapping Information
Human SNP ID rs4710520
Human chromosome chr6
Human SNP position 65468587
Pig chromosome chr1
Pig SNP position 52279630
2.Annotation Information
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region6q12
Chromosome idchr6
Chromosome position65468587
Reported geneNR
Mapped geneEYS
Upstream gene id
Downstream gene id
SNP gene ids346007
Upstream gene distance
Downstream gene distance
SNP risk allelers4710520-C
SNPsrs4710520
Merged0
SNP id current4710520
Contextintron_variant
Intergenic0
Allele frequency0.00803558
P value0.000006
Pvalue mlog5.22184874961635
P value text(IGP36)
Or beta2.107
%95 Ci[1.2-3.02] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region6q12
Chromosome idchr6
Chromosome position65468587
Reported geneNR
Mapped geneEYS
Upstream gene id
Downstream gene id
SNP gene ids346007
Upstream gene distance
Downstream gene distance
SNP risk allelers4710520-C
SNPsrs4710520
Merged0
SNP id current4710520
Contextintron_variant
Intergenic0
Allele frequency0.00804562
P value0.000003
Pvalue mlog5.52287874528033
P value text(IGP37)
Or beta2.1675
%95 Ci[1.26-3.08] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848
PubMed ID23382691
JournalPLoS Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/23382691
StudyLoci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
Disease/TraitIgG glycosylation
Initial sample2,247 European ancestry individuals
Replication sampleNA
Region6q12
Chromosome idchr6
Chromosome position65468587
Reported geneNR
Mapped geneEYS
Upstream gene id
Downstream gene id
SNP gene ids346007
Upstream gene distance
Downstream gene distance
SNP risk allelers4710520-C
SNPsrs4710520
Merged0
SNP id current4710520
Contextintron_variant
Intergenic0
Allele frequency0.00803558
P value0.000005
Pvalue mlog5.30102999566398
P value text(IGP38)
Or beta2.1251
%95 Ci[1.21-3.04] unit increase
PlatformIllumina [~ 2500000] (imputed)
CNVN
Mapped traitserum IgG glycosylation measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005193
Study accessionGCST001848