SNP Detail For rs4698412
1.Mapping Information
Human SNP ID rs4698412
Human chromosome chr4
Human SNP position 15735725
Pig chromosome chr8
Pig SNP position 10694284
2.Annotation Information
PubMed ID21084426
JournalHum Mol Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/21084426
StudyGenome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson__s disease in the European population.
Disease/TraitParkinson__s disease
Initial sample1,039 European ancestry cases, 1,984 European ancestry controls
Replication sample3,232 European ancestry cases, 7,064 European ancestry controls
Region4p15.32
Chromosome idchr4
Chromosome position15735725
Reported geneBST1
Mapped geneBST1
Upstream gene id
Downstream gene id
SNP gene ids683
Upstream gene distance
Downstream gene distance
SNP risk allelers4698412-A
SNPsrs4698412
Merged0
SNP id current4698412
Contextintron_variant
Intergenic0
Allele frequency0.55
P value0.000002
Pvalue mlog5.69897000433601
P value text
Or beta1.14
%95 Ci[1.08-1.20]
PlatformIllumina [492929]
CNVN
Mapped traitParkinson__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002508
Study accessionGCST000874
PubMed ID22451204
JournalAnn Neurol
Linkwww.ncbi.nlm.nih.gov/pubmed/22451204
StudyMeta-analysis of Parkinson__s disease: identification of a novel locus, RIT2.
Disease/TraitParkinson__s disease
Initial sample4,238 European ancestry cases, 4,239 European ancestry controls
Replication sample3,738 European ancestry cases, 2,111 European ancestry controls
Region4p15.32
Chromosome idchr4
Chromosome position15735725
Reported geneBST1
Mapped geneBST1
Upstream gene id
Downstream gene id
SNP gene ids683
Upstream gene distance
Downstream gene distance
SNP risk allelers4698412-?
SNPsrs4698412
Merged0
SNP id current4698412
Contextintron_variant
Intergenic0
Allele frequencyNR
P value0.0000003
Pvalue mlog6.52287874528033
P value text
Or beta1.14
%95 Ci[NR]
PlatformIllumina [2500000] (imputed)
CNVN
Mapped traitParkinson__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0002508
Study accessionGCST001430