SNP Detail For rs4693977
1.Mapping Information
Human SNP ID rs4693977
Human chromosome chr4
Human SNP position 88932928
Pig chromosome chr8
Pig SNP position 139644944
2.Annotation Information
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q22.1
Chromosome idchr4
Chromosome position88932928
Reported geneFAM13A
Mapped geneLOC105377327, FAM13A
Upstream gene id
Downstream gene id
SNP gene ids105377327, 10144
Upstream gene distance
Downstream gene distance
SNP risk allelers4693977-A
SNPsrs4693977
Merged0
SNP id current4693977
Contextintron_variant
Intergenic0
Allele frequency0.298
P value0.0000006
Pvalue mlog6.22184874961635
P value text
Or beta0.048
%95 CiNR unit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitforced expiratory volume, response to bronchodilator
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004314, http://purl.obolibrary.org/obo/GO_0097366
Study accessionGCST003262
PubMed ID26634245
JournalBMC Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/26634245
StudyA genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
Disease/TraitPost bronchodilator FEV1/FVC ratio
Initial sample10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals
Replication sampleNA
Region4q22.1
Chromosome idchr4
Chromosome position88932928
Reported geneFAM13A
Mapped geneLOC105377327, FAM13A
Upstream gene id
Downstream gene id
SNP gene ids105377327, 10144
Upstream gene distance
Downstream gene distance
SNP risk allelers4693977-A
SNPsrs4693977
Merged0
SNP id current4693977
Contextintron_variant
Intergenic0
Allele frequency0.301
P value0.0000002
Pvalue mlog6.69897000433601
P value text
Or beta0.01
%95 Ciunit decrease
PlatformIllumina [NR] (imputed)
CNVN
Mapped traitresponse to bronchodilator, FEV/FEC ratio
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_0097366, http://www.ebi.ac.uk/efo/EFO_0004713
Study accessionGCST003264