SNP Detail For rs4680534
1.Mapping Information
Human SNP ID rs4680534
Human chromosome chr3
Human SNP position 159981157
Pig chromosome chr13
Pig SNP position 108058424
2.Annotation Information
PubMed ID19525953
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/19525953
StudyMeta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
Disease/TraitMultiple sclerosis
Initial sample2,624 European ancestry cases, 7,220 European ancestry controls
Replication sample2,215 European ancestry cases, 2,116 European ancestry controls
Region3q25.33
Chromosome idchr3
Chromosome position159981157
Reported geneIL12A
Mapped geneIL12A-AS1
Upstream gene id
Downstream gene id
SNP gene ids101928376
Upstream gene distance
Downstream gene distance
SNP risk allelers4680534-C
SNPsrs4680534
Merged0
SNP id current4680534
Contextintron_variant
Intergenic0
Allele frequency0.37
P value0.000006
Pvalue mlog5.22184874961635
P value text
Or beta1.12
%95 Ci[1.02-1.22]
PlatformAffymetrix, Illumina [~ 2560000] (imputed)
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST000424