Human SNP ID | rs4663476 |
---|---|
Human chromosome | chr2 |
Human SNP position | 234692420 |
Pig chromosome | chr15 |
Pig SNP position | 149358547 |
PubMed ID | 22566498 |
---|---|
Journal | Hypertension |
Link | www.ncbi.nlm.nih.gov/pubmed/22566498 |
Study | Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. |
Disease/Trait | Response to angiotensin II receptor blocker therapy |
Initial sample | 198 European ancestry hypertensive individuals, 193 African American hypertensive individuals |
Replication sample | NA |
Region | 2q37.1 |
Chromosome id | chr2 |
Chromosome position | 234692420 |
Reported gene | AC010148.1 |
Mapped gene | LOC105373936 - LOC101927896 |
Upstream gene id | 105373936 |
Downstream gene id | 101927896 |
SNP gene ids | |
Upstream gene distance | 59715 |
Downstream gene distance | 100784 |
SNP risk allele | rs4663476-G |
SNPs | rs4663476 |
Merged | 0 |
SNP id current | 4663476 |
Context | intron_variant |
Intergenic | 1 |
Allele frequency | NR |
P value | 0.000008 |
Pvalue mlog | 5.09691001300805 |
P value text | (AA) |
Or beta | 1.23 |
%95 Ci | [0.66-1.80] unit decrease |
Platform | Affymetrix [~ 2300000] (imputed) |
CNV | N |
Mapped trait | response to candesartan, hypertension |
Mapped trait URI | http://purl.obolibrary.org/obo/GO_1901556, http://www.ebi.ac.uk/efo/EFO_0000537 |
Study accession | GCST001520 |