SNP Detail For rs4663476
1.Mapping Information
Human SNP ID rs4663476
Human chromosome chr2
Human SNP position 234692420
Pig chromosome chr15
Pig SNP position 149358547
2.Annotation Information
PubMed ID22566498
JournalHypertension
Linkwww.ncbi.nlm.nih.gov/pubmed/22566498
StudyGenomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.
Disease/TraitResponse to angiotensin II receptor blocker therapy
Initial sample198 European ancestry hypertensive individuals, 193 African American hypertensive individuals
Replication sampleNA
Region2q37.1
Chromosome idchr2
Chromosome position234692420
Reported geneAC010148.1
Mapped geneLOC105373936 - LOC101927896
Upstream gene id105373936
Downstream gene id101927896
SNP gene ids
Upstream gene distance59715
Downstream gene distance100784
SNP risk allelers4663476-G
SNPsrs4663476
Merged0
SNP id current4663476
Contextintron_variant
Intergenic1
Allele frequencyNR
P value0.000008
Pvalue mlog5.09691001300805
P value text(AA)
Or beta1.23
%95 Ci[0.66-1.80] unit decrease
PlatformAffymetrix [~ 2300000] (imputed)
CNVN
Mapped traitresponse to candesartan, hypertension
Mapped trait URIhttp://purl.obolibrary.org/obo/GO_1901556, http://www.ebi.ac.uk/efo/EFO_0000537
Study accessionGCST001520