SNP Detail For rs4660293
1.Mapping Information
Human SNP ID rs4660293
Human chromosome chr1
Human SNP position 39562508
Pig chromosome chr6
Pig SNP position 88470891
2.Annotation Information
PubMed ID20686565
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/20686565
StudyBiological, clinical and population relevance of 95 loci for blood lipids.
Disease/TraitHDL cholesterol
Initial sample99,900 European ancestry individuals
Replication sampleNA
Region1p34.3
Chromosome idchr1
Chromosome position39562508
Reported geneMACF1, PABPC4
Mapped genePABPC4
Upstream gene id
Downstream gene id
SNP gene ids8761
Upstream gene distance
Downstream gene distance
SNP risk allelers4660293-G
SNPsrs4660293
Merged0
SNP id current4660293
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.23
P value0.0000000004
Pvalue mlog9.39794000867203
P value text
Or beta0.48
%95 Ci[0.3-0.66] mg/dL decrease
PlatformAffymetrix, Illumina, Perlegen [~ 2600000] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST000755
PubMed ID24097068
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/24097068
StudyDiscovery and refinement of loci associated with lipid levels.
Disease/TraitHDL cholesterol
Initial sample94,595 European ancestry individuals
Replication sample93,982 European ancestry individuals
Region1p34.3
Chromosome idchr1
Chromosome position39562508
Reported genePABPC4
Mapped genePABPC4
Upstream gene id
Downstream gene id
SNP gene ids8761
Upstream gene distance
Downstream gene distance
SNP risk allelers4660293-G
SNPsrs4660293
Merged0
SNP id current4660293
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency0.24
P value0.000000000000000003
Pvalue mlog17.5228787452803
P value text
Or beta0.035
%95 Ci[NR] unit decrease
PlatformNR [NR] (imputed)
CNVN
Mapped traithigh density lipoprotein cholesterol measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0004612
Study accessionGCST002223