SNP Detail For rs4646284
1.Mapping Information
Human SNP ID rs4646284
Human chromosome chr6
Human SNP position 160160512
Pig chromosome chr1
Pig SNP position 9138471
2.Annotation Information
PubMed ID26034056
JournalCancer Discov
Linkwww.ncbi.nlm.nih.gov/pubmed/26034056
StudyA large multi-ethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.
Disease/TraitProstate cancer
Initial sample6,406 European ancestry cases, 601 African American cases, 288 East Asian ancestry cases, 488 Latino cases30,866 European ancestry controls, 1,650 African American controls, 2,938 East Asian ancestry controls, 3,141 Latino controls
Replication sample4,599 European ancestry cases, 2,265 African American cases, 2,940 European ancestry controls, 2,414 African American controls
Region6q25.3
Chromosome idchr6
Chromosome position160160512
Reported geneSLC22A2, SLC22A1
Mapped geneSLC22A1 - SLC22A2
Upstream gene id6580
Downstream gene id6582
SNP gene ids
Upstream gene distance1314
Downstream gene distance56250
SNP risk allelers4646284-TG
SNPsrs4646284
Merged
SNP id current4646284
Contextdownstream_gene_variant
Intergenic1
Allele frequency0.298
P value1E-19
Pvalue mlog19
P value text
Or beta1.18
%95 Ci[1.14-1.22]
PlatformAffymetrix [up to 19977088] (imputed)
CNVN
Mapped traitprostate carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001663
Study accessionGCST002944