SNP Detail For rs4613763
1.Mapping Information
Human SNP ID rs4613763
Human chromosome chr5
Human SNP position 40392626
Pig chromosome chr16
Pig SNP position 26701940
2.Annotation Information
PubMed ID18587394
JournalNat Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/18587394
StudyGenome-wide association defines more than 30 distinct susceptibility loci for Crohn__s disease.
Disease/TraitCrohn__s disease
Initial sample3,230 European ancestry cases, 4,829 European ancestry controls
Replication sample1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls
Region5p13.1
Chromosome idchr5
Chromosome position40392626
Reported genePTGER4
Mapped geneLOC105374736 - LOC105374737
Upstream gene id105374736
Downstream gene id105374737
SNP gene ids
Upstream gene distance46071
Downstream gene distance207254
SNP risk allelers4613763-C
SNPsrs4613763
Merged0
SNP id current4613763
Contextintergenic_variant
Intergenic1
Allele frequency0.13
P value7E-27
Pvalue mlog26.1549019599857
P value text
Or beta1.32
%95 Ci[NR]
PlatformAffymetrix, Illumina [635547] (imputed)
CNVN
Mapped traitCrohn__s disease
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0000384
Study accessionGCST000207
PubMed ID21833088
JournalNature
Linkwww.ncbi.nlm.nih.gov/pubmed/21833088
StudyGenetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Disease/TraitMultiple sclerosis
Initial sample9,772 European ancestry cases, 16,849 European ancestry controls
Replication sample4,218 European ancestry cases, 7,296 European ancestry controls
Region5p13.1
Chromosome idchr5
Chromosome position40392626
Reported genePTGER4
Mapped geneLOC105374736 - LOC105374737
Upstream gene id105374736
Downstream gene id105374737
SNP gene ids
Upstream gene distance46071
Downstream gene distance207254
SNP risk allelers4613763-G
SNPsrs4613763
Merged0
SNP id current4613763
Contextintergenic_variant
Intergenic1
Allele frequencyNR
P value0.0000000000000003
Pvalue mlog15.5228787452803
P value text
Or beta1.2
%95 Ci[1.18-1.22]
PlatformIllumina [465434]
CNVN
Mapped traitmultiple sclerosis
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0003885
Study accessionGCST001198