SNP Detail For rs4589502
1.Mapping Information
Human SNP ID rs4589502
Human chromosome chr15
Human SNP position 66862731
Pig chromosome chr1
Pig SNP position 182561398
2.Annotation Information
PubMed ID24658283
JournalCarcinogenesis
Linkwww.ncbi.nlm.nih.gov/pubmed/24658283
StudyA genome-wide gene-environment interaction analysis for tobacco smoke and lung cancer susceptibility.
Disease/TraitLung cancer (smoking interaction)
Initial sample1,506 Han Chinese ancestry smoker cases, 825 Han Chinese ancestry non-smoker cases, 1,309 Han Chinese ancestry smoker controls, 1,768 Han Chinese ancestry non-smoker controls
Replication sample912 Han Chinese ancestry smoker cases, 622 Han Chinese ancestry non-smoker cases, 572 Han Chinese ancestry smoker controls, 917 Han Chinese ancestry non-smoker controls
Region15q22.31
Chromosome idchr15
Chromosome position66862731
Reported geneSMAD6, SMAD3
Mapped geneLOC105376718
Upstream gene id
Downstream gene id
SNP gene ids105376718
Upstream gene distance
Downstream gene distance
SNP risk allelers4589502-T
SNPsrs4589502
Merged0
SNP id current4589502
Contextnon_coding_transcript_exon_variant
Intergenic0
Allele frequency
P value0.000004
Pvalue mlog5.39794000867203
P value text
Or beta1.55
%95 Ci[1.29-1.87]
PlatformAffymetrix [591370]
CNVN
Mapped traitlung carcinoma
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001071
Study accessionGCST002392