SNP Detail For rs4527850
1.Mapping Information
Human SNP ID rs4527850
Human chromosome chr8
Human SNP position 133184606
Pig chromosome chr4
Pig SNP position 8184139
2.Annotation Information
PubMed ID23300278
JournalDiabetes
Linkwww.ncbi.nlm.nih.gov/pubmed/23300278
StudyGenome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.
Disease/TraitType 2 diabetes
Initial sample842 Punjabi Sikh ancestry cases, 774 Punjabi Sikh ancestry controls
Replication sampleup to 2,512 Punjabi Sikh ancestry cases and 3,201 Punjabi Sikh ancestry controls, up to 16,128 South Asian ancestry cases and 23,846 South Asian ancestry controls, up to 16,746 East Asian ancestry cases and 16,961 East Asian ancestry controls, up to 8,130
Region8q24.22
Chromosome idchr8
Chromosome position133184606
Reported geneWISP1
Mapped geneLOC105375769 - WISP1
Upstream gene id105375769
Downstream gene id8840
SNP gene ids
Upstream gene distance18273
Downstream gene distance6433
SNP risk allelers4527850-T
SNPsrs4527850
Merged0
SNP id current4527850
Contextintergenic_variant
Intergenic1
Allele frequency0.75
P value0.000002
Pvalue mlog5.69897000433601
P value text(Punjabi Sikhs)
Or beta1.23
%95 Ci[1.13 - 1.34]
PlatformIllumina [1232008] (imputed)
CNVN
Mapped traittype II diabetes mellitus
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0001360
Study accessionGCST001809