SNP Detail For rs4518370
1.Mapping Information
Human SNP ID rs4518370
Human chromosome chr5
Human SNP position 82884487
Pig chromosome chr2
Pig SNP position 93279844
2.Annotation Information
PubMed ID25057126
JournalJ Med Genet
Linkwww.ncbi.nlm.nih.gov/pubmed/25057126
StudyMeta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.
Disease/TraitOsteoarthritis biomarkers
Initial sampleup to 4,654 European ancestry individuals
Replication sample964 European ancestry individuals
Region5q14.2
Chromosome idchr5
Chromosome position82884487
Reported geneSCARNA18, XRCC4, TMEM167A
Mapped geneLINC01338 - LOC105379051
Upstream gene id102546175
Downstream gene id105379051
SNP gene ids
Upstream gene distance24651
Downstream gene distance28880
SNP risk allelers4518370-G
SNPsrs4518370
Merged0
SNP id current4518370
Contextintergenic_variant
Intergenic1
Allele frequency0.75
P value0.000001
Pvalue mlog6
P value text(uCTX-II)
Or beta0.11
%95 Ci[NR] unit decrease
PlatformIllumina [up to 1961964] (imputed)
CNVN
Mapped traitosteoarthritis biomarker measurement
Mapped trait URIhttp://www.ebi.ac.uk/efo/EFO_0005890
Study accessionGCST002540